AI could predict cognitive decline leading to Alzheimer’s disease in the next five years

A team of scientists has successfully trained a new artificial intelligence (AI) algorithm to make accurate predictions regarding cognitive decline leading to Alzheimer’s disease. Dr. Mallar Chakravarty, a computational neuroscientist at the Douglas Mental Health University Institute, and his colleagues from the University of Toronto and the Centre for Addiction and Mental Health, designed an algorithm that learns signatures from […]

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To help beat heart disease, stay upbeat

(HealthDay)—Optimism and a sense of purpose can improve your heart health, new research suggests. Psychological well-being has cardiovascular benefits because people with a positive outlook are more inclined to lead a healthy lifestyle, the researchers concluded. Upbeat people are more likely to eat well, engage in physical activity, maintain social connections and avoid negative behaviors, prior research has shown. This […]

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Exposure to arsenic, lead, copper and cadmium linked to increased risk of heart disease

Exposure to arsenic, lead, copper and cadmium is associated with an increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published by The BMJ today. In recent years, exposure to environmental toxic metals such as arsenic, lead, copper, and mercury have become a major global health concern. Arsenic and cadmium, for example, are […]

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Effects of deep brain stimulation in patients with Parkinson’s disease

Researchers at Universitätsmedizin Berlin have studied motor and cognitive effects of deep brain stimulation in patients with Parkinson’s disease. Their results show that the adverse cognitive effects of deep brain stimulation are linked to a different neural pathway than that responsible for the treatment’s desired motor effects. This finding will help optimize treatments for patients with Parkinson’s disease. Results from […]

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More protein after weight loss may reduce fatty liver disease

Increasing the amount of protein in the diet may reduce the liver’s fat content and lower the risk of diabetes in people with nonalcoholic fatty liver disease (NAFLD). The study is published ahead of print in the American Journal of Physiology—Endocrinology and Metabolism. NAFLD—sometimes referred to as a “fatty liver”—occurs when more than 5 percent of the liver’s total weight […]

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pH imbalance in brain cells may contribute to Alzheimer’s disease

Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer’s disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells. Astrocytes work to clear so-called amyloid beta proteins from the spaces between neurons, but decades of evidence has shown […]

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Next-generation ALS drug silences inherited form of the disease in animal models

NIH-funded researchers delayed signs of amyotrophic lateral sclerosis (ALS) in rodents by injecting them with a second-generation drug designed to silence the gene, superoxide dismutase 1 (SOD1). The results, published in the Journal of Clinical Investigation, suggest the newer version of the drug may be effective at treating an inherited form of the disease caused by mutations in SOD1. Currently, […]

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