ClinEpiDB data resource releases childhood malnutrition and intestinal disease study

As the big data revolution continues to evolve, access to data that cut across many disciplines becomes increasingly valuable. In the field of public health, one barrier to sharing data is the need for users to fully comprehend complex methodological details and data variables in order to properly conduct analyses. The Clinical Epidemiology Database, ClinEpiDB.org aims to address these barriers […]

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Therapy adherence for inflammatory bowel disease lower in the educated

(HealthDay)—Nonadherence to inflammatory bowel disease (IBD) treatment is more common among wealthier, more educated patients, according to a study published online March 18 in JGH Open. Sanjeevani K. Tomar, from the All India Institute of Medical Sciences in New Delhi, and colleagues sought to identify the rates and predictors of nonadherence to medications in IBD among 266 patients (204 with […]

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Pediatric onset multiple sclerosis study examines baffling, often-overlooked disease

Seemingly overnight, healthy children develop mysterious, potentially disabling symptoms. When children finally receive a diagnosis, often after weeks of tests and office and hospital visits, the parents may be shocked to learn that they have multiple sclerosis—a potentially disabling autoimmune disease once believed to affect only adults. “For many years, the tagline for MS was that it was the ‘leading […]

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Dry eye disease and diabetes: New study reveals scale of issue and need for screening

Credit: Shutterstock Diabetes is a debilitating health condition which is expected to reach epidemic proportions in the next 20 years. According to the World Health Organisation, 108m people around the world had diabetes in 1980; by 2014 that figure was 422m. Three years later in 2017, 425m people worldwide were living with the disease and this figure is expected to […]

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Is kidney failure a man’s disease?

A new analysis of the ERA-EDTA Registry reveals a striking gender difference in the incidence and prevalence of end-stage renal disease. Two thirds of all dialysis patients in Europe are male. It seems beyond hormonal effects that hypertension, diabetes and glomerulonephritis/sclerosis are the main driver of the gender gap. However, it is possible to prevent and treat hypertension and diabetes […]

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Gene-edited disease monkeys cloned in China

The first cohort of five gene-edited monkey clones made from fibroblasts of a monkey with disease phenotypes were born recently at the Institute of Neuroscience (ION) of the Chinese Academy of Sciences (CAS) in Shanghai. The expression of BMAL1, a core circadian regulatory transcription factor, was knocked out in the donor monkey using CRISPR/Cas9-mediated gene editing at the embryo stage, […]

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Liver transplants double for alcohol-related liver disease

The proportion of U.S. liver transplants for alcohol-associated liver disease (ALD) has doubled in the last 15 years, in part due to broader acceptance of waiving the mandated period of sobriety before transplants for this population, according to a study by researchers at UC San Francisco. However, the study showed ongoing regional geographic variations in liver transplant rates for ALD […]

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