Scientists discover a new way to control blood pressure

New, improved ways to fight hypertension and low blood pressure may be in the offing, thanks to a discovery of how blood pressure is controlled. National University of Singapore researchers have found a new means of controlling blood pressure that involves the protein galectin-1, present in blood vessels and various other tissues. The researchers showed that galectin-1 reduces the activity […]

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Surgical technique improves sensation, control of prosthetic limb

Humans can accurately sense the position, speed, and torque of their limbs, even with their eyes shut. This sense, known as proprioception, allows humans to precisely control their body movements. Despite significant improvements to prosthetic devices in recent years, researchers have been unable to provide this essential sensation to people with artificial limbs, limiting their ability to accurately control their […]

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UNICEF ‘muted’ on tobacco control for children

The tobacco industry manipulated the renowned children’s rights agency UNICEF for more than a dozen years, from 2003 until at least 2016, during which time UNICEF’s focus on children’s rights to a tobacco-free life was reduced, according to previously secret documents uncovered by UC San Francisco. The research appears April 30, 2018, in Pediatrics, the journal of the American Academy […]

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Selection of a pyrethroid metabolic enzyme CYP9K1 by malaria control activities

Researchers from LSTM, with partners from a number of international institutions, have shown the rapid selection of a novel P450 enzyme leading to insecticide resistance in a major malaria vector. In a paper published in PNAS the team of researchers led by LSTM’s Professor Janet Hemingway describe how operational malaria control activities, and a move back to pyrethroid based indoor […]

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New mathematical parameters to model the impact of Wolbachia infection for disease control

LSTM’s Dr. Gabriela Gomes is senior author on a new study which outlines the importance of using variation in mosquito susceptibility as a parameter in mathematical modelling to realistically assess the impact of Wolbachia infection on disease transmission. The Aedes aegypti mosquito is a disease vector for a number of arboviruses including, chikungunya, dengue and Zika. Wolbachia, a bacterial symbiont, […]

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Efficient control of leukaemia with treatment by dual immune-checkpoint blockade

Chronic lymphocytic leukaemia (CLL) is a haematological malignancy that originates in the blood-forming cells of the bone marrow and spreads to other organs through the bloodstream. When infiltrating tissues, CLL cells come in contact with healthy cells, including immune cells. To ensure their survival and growth, CLL cells are able to establish a microenvironment in which the immune response is […]

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