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The gut has a population of organisms that live within in it, called the gut microbiome, which are linked to human health and disease. Recent studies have shown that assessing the genetic changes in fecal samples can accurately reflect the status of the gut microbiome, and may be useful for the early diagnosis of diseases. A group of researchers from […]
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The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published today in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants that signal an increased risk of colon cancer. The study, led by a team of investigators at Fred Hutchinson Cancer Research Center, also has identified the first rare protective […]
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A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers. The finding, published online Oct. 5 in the journal Gastroenterology, describes an association between antibodies to H. pylori bacteria and an increased risk of colorectal cancers, although it does not […]
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The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its over-expression leads to excessive cell proliferation. A new study carried out by a team led by Professor Heiko Hermeking at the Institute of Pathology […]
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Putting nurses in charge of colorectal cancer surveillance instead of doctors has shown to reduce the number of unnecessary colonoscopies and the number of cases progressing to cancer. The South Australian audit of 732 colonoscopies over three months in 2015 found that 97 per cent of procedures adhered to Australian guidelines in the nurse-led model while compliance was just 83 […]
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Logically, it would seem that more follow-up testing of cancer patients must be better—but this is not the case for patients who undergo surgery for colorectal cancer. This is an important conclusion from a study in which 2,509 patients with colorectal cancer were offered two and five follow-up tests in the form of CT scans combined with a blood test […]
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