Bioluminescent deep-sea creatures illuminate the effectiveness of new cancer therapies

Researchers at the Keck School of Medicine of USC have developed a new laboratory tool, which is poised to improve the development and effectiveness of a burgeoning group of therapies that use patients’ immune systems to fight cancer with genetically engineered CAR-T cells. Called the Topanga assay, the tool was inspired by the beauty of Topanga Beach in Malibu and […]

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Prostate cancer: Starving out the enemy

An old military tactic, widely used in Roman and medieval times, is now being put to good use in cancer research. The idea is that if you starve out your enemy—they will either submit or die. And in the race to develop treatments for prostate cancer, starving out those hostile cancer cells is proving effective. Metabolic biologist at the University […]

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Japanese study finds concerning trends in cervical cancer and treatment response

Cervical cancer rates can be greatly reduced through preventive measures against the human papillomavirus (HPV) along with proactive cancer screening. Japan may be showing how ignoring that knowledge could prove hazardous, as it is the only advanced economy in which the cervical cancer rate is increasing. New research adds further nuance to this situation. Researchers centered at Osaka University examined […]

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Important signaling pathway in breast cancer revealed

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences (PNAS) that a particular signaling pathway in breast cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. Inhibiting the pathway with drugs could become a strategy for eliminating the cancer cells. In breast cancer, one of the most common cancers in women, tumors contain a […]

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Cancer patients can quit smoking through lengthened medication time, counseling support

Quitting smoking can significantly improve the effectiveness of cancer treatment, according to the U.S. Surgeon General, yet almost half of cancer patients continue to smoke after they’ve been diagnosed. A new study from Northwestern Medicine and the Abramson Cancer Center at the University of Pennsylvania found cancer patients have better success quitting and are not as prone to relapsing one year later […]

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Innovative diagnostic test could revolutionise cervical cancer screening

Coinciding with Cervical Cancer Prevention Week, researchers at St George’s are working on a field study to fine-tune an exciting new method of human papilloma virus testing that could revolutionise care for women in low and middle income countries. The research team have partnered with molecular diagnostics firm QuantuMDx for the study, using the company’s Q-POC platform and its human […]

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Liver cancer patients can be treated for Hep C infection

A large, multi-center study refutes earlier suggestions that antiviral drugs for treating hepatitis C may lead to a higher recurrence of liver cancer. Researchers at UT Southwestern Medical Center studied the records of patients who had been successfully treated for liver cancer at 31 medical centers in North America, comparing those who were and were not given direct-acting antivirals for […]

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Research team documents potential new treatment path for breast cancer

Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]

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Breast cancer up to five times more likely to metastasize even 10 years after childbirth

A study by researchers at University of Colorado Cancer Center and Oregon Health & Science University published today in the Journal of the American Medical Association Network shows that breast cancers diagnosed in young women within 10 years of giving birth are more likely to metastasize, and thus more likely to cause death, than breast cancers in young women who […]

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