AUA: Atenolol linked to drop in low-, intermediate-risk prostate cancer

(HealthDay)—Atenolol is associated with a reduction in incident intermediate- and low-risk prostate cancer (PCa), according to a study presented at the annual meeting of the American Urological Association, held from May 3 to 6 in Chicago. Ali Zahalka, M.D., Ph.D., from the Albert Einstein College of Medicine and Montefiore Medical Center in Bronx, New York, and colleagues conducted a retrospective […]

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Global HER2 testing survey raises questions about priorities for breast cancer resources

A global survey of HER2 testing has raised questions about how resources should be spent on potentially lifesaving HER2 targeted therapies for breast cancer, especially in poorer countries. The results were presented at the ESMO Breast Cancer Congress 2019, Berlin, 2-4 May 2019. The ONCOLLEGE-001 internet-based survey of HER2 testing in 45 countries has highlighted major access and affordability issues […]

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Rapidly detecting cancer markers for diagnosis

Researchers at Okayama University report in the journal Sensors and Actuators B: Chemical that terahertz radiation can be used to rapidly detect makers for breast-cancer cells. The scientists present a technique that makes use of the binding properties of aptamers, synthetic organic molecules acting as probes for cancer cells. Breast cancer is the most common cancer in women. Detecting it […]

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Shining light on rare nerve tumors illuminates a fresh path for fighting cancer

When a protein named “Merlin” fails to do its job, people can develop slow-growing, life-disrupting auditory nerve tumors that can disrupt their hearing and balance. This rare condition is called neurofibromatosis 2 (NF2). Now scientists at Cincinnati Children’s have discovered much more about how Merlin does its job—by working behind the scenes through a network of more than 50 other […]

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Conception by IVF may increase risk for rare childhood cancer

(HealthDay)—There is a small association between conception by in vitro fertilization (IVF) and childhood cancer, particularly hepatic tumors, according to a study published online April 1 in JAMA Pediatrics. Logan G. Spector, Ph.D., from the University of Minnesota in Minneapolis, and colleagues used data from the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System on IVF cycles that resulted […]

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Loss of a DNA repair system creates a unique vulnerability in many cancer types

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes’ activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies. Reporting in Nature, researchers led by members of the Cancer Dependency […]

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Inhaled nanoparticles could treat lung cancer

QUT pharmaceutical scientist Dr. Nazrul Islam, from School of Clinical Sciences, said lung cancer was one of the most common cancers globally and one of the deadliest, being a leading cause of cancer deaths. He said chitosan had long been investigated for drug delivery and medical applications. It is made from refined crustacean (prawns, crabs, lobster) shells and was an […]

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Researchers develop treatment that turns tumors into cancer vaccine factories

Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, injecting immune stimulants directly into a tumor to teach the immune system to destroy it and other tumor cells throughout the body. The “in situ vaccination” worked so well in patients with advanced-stage lymphoma that it is also undergoing trials in breast and head and neck cancer patients, […]

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Metastatic prostate cancer may have its own biomarker, research finds

Prostate cancer can grow slowly and pose little threat to patients, or it can metastasize quickly, causing severe pain and death. But as of now, it’s nearly impossible to determine which type of cancer a patient has during the early stages. Now, University at Buffalo researchers and scientists from Moscow State University are collaborating to determine how a biomarker for […]

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New therapy approach points to potential treatment of liver cancer patients with hepatitis B virus infection

Researchers from Duke-NUS Medical School, Singapore General Hospital (SGH) and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma (HCC), a commonly occurring liver cancer. The treatment was also individualised, as T cells that were engineered were specific to the patients. The approach […]

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