Novel genetic signature that can predict some kinds of breast cancer is identified

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases. The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, […]

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Healthy diet may avert nutritional problems in head, neck cancer patients

At least 90 percent of head and neck cancer patients develop symptoms that affect their ability or desire to eat, because of either the tumor itself or the surgery or radiation used to treat it. These problems, called nutrition impact symptoms, have wide-ranging negative effects on patients’ physical and mental health and quality of life. However, patients who eat foods […]

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Study examines causes of death in US breast cancer survivors

Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients with breast cancer. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Of […]

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Potential new cancer treatment a step closer

QIMR Berghofer researchers have discovered a potential new cancer immunotherapy target that involves switching off a regulatory cell to stop tumors growing and spreading. The study findings have been published today in Cancer Discovery, a journal of the American Association for Cancer Research. Senior researcher and head of QIMR Berghofer’s Cancer Immunoregulation and Immunotherapy Laboratory, Associate Professor Michele Teng, said […]

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A common insulin signaling pathway across cancer and diabetes

An oncology researcher has made an unexpected contribution to the understanding of type 2 diabetes. In results published in Science Advances, Patrick Hu, M.D., associate professor of medicine at Vanderbilt University Medical Center, found a protein that modulates a signaling pathway often targeted by cancer therapies is also required for insulin biogenesis. Hu and colleagues showed a protein controlling the […]

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Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study. “This agent has shown in clinical trials to be effective in delaying cancer growth beyond established […]

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The high cost challenge of personalised screening for bowel cancer

Personalised screening could improve the diagnosis of bowel cancer and re-shape the future of Australia’s National Bowel Cancer Screening Program (NBCSP), according to new research at The University of Western Australia. The study, published today in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research, hopes to improve health outcomes by targeting screening at those […]

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New cancer treatment not as toxic as others

A QIMR Berghofer study has identified how a newly approved blood cancer drug works and found the treatment is better than other drugs at targeting cancer stem cells while causing minimal damage to healthy cells. The long-acting form of the drug Interferon alpha was approved for use in Australia in mid-2018 to treat patients with a type of blood cancer, […]

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