cancer Archives - Page 22 of 26 - Family Medicine News

Peripheral neuropathy common in childhood cancer survivors

18.05.2018 Health Problems

(HealthDay)—Childhood cancer survivors frequently have clinical abnormalities attributable to peripheral neuropathy, according to a study published online May 14 in JAMA Neurology. Tejaswi Kandula, M.B.B.S., from the University of New South Wales in Sidney, and colleagues recruited cancer survivors who were treated with chemotherapy for extracranial malignancy before age 17 years and compared them with healthy age-matched controls. One hundred […]

Genetic fixer-uppers may predict bladder cancer prognosis

17.05.2018 Health Problems

Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers. The researchers found that bladder cancer patients who had mutations in their ATM or RB1 genes—proteins that help repair DNA damage when they’re functioning normally—tended not to live as long as patients without the […]

Discovery means individualized ovarian, brain cancer therapies

17.05.2018 Health Problems

Mayo Clinic researchers have discovered that a molecular communication pathway—thought to be defective in cancer—is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers. This discovery enabled researchers to develop an algorithm to predict treatment effectiveness in individual patients. The findings appear in the Journal of the National Cancer Institute. […]

Colon cancer cells use mysterious RNA strands to avoid cell death

17.05.2018 Health Problems

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other RNAs, the intriguing strands do not appear to encode proteins and are termed “long non-coding RNAs” or “lincRNAs.”A new study showed some lincRNAs could be targeted by drug developers to halt colon […]

Reducing cholesterol could enhance T-cell cancer immunotherapy

17.05.2018 Health Problems

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer. The team, led by Qing Yi, MD, Ph.D., of Cleveland Clinic Lerner Research Institute studied T-cell transfer, which has shown great success in recent years. Dr. Yi previously showed that a specific […]

Cancer treatment changes cancer cells into normal ones

11.05.2018 Health Problems

BGN Technologies, the technology-transfer company of Ben-Gurion University of the Negev (BGU), announced that a research group led by Prof. Varda Shoshan-Barmatz of the BGU Department of Life Sciences and the National Institute for Biotechnology in the Negev, is developing a new molecule to treat cancer that inhibits cancer cell growth and changes these cells back to normal ones. “Although […]

Scientists screen molecules for promise as new prostate cancer drugs

11.05.2018 Health Problems

Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be developed into new anti-cancer drugs. The research team from the Departments of Pharmacy & Pharmacology and Chemistry are studying a protein called α-methylacyl-CoA racemase (AMACR) as a potential […]

Nodal metastasis risk up when cancer is directly on the lip

11.05.2018 Health Problems

(HealthDay)—The risk of nodal metastasis is five-fold greater for skin cancer on the vermilion lip versus the cutaneous lip, according to a study published online May 2 in JAMA Dermatology. David M. Wang, from Case Western Reserve University in Cleveland, and colleagues compared differences in risks of recurrence, metastasis, and death from cutaneous squamous cell carcinoma (cSCC) on the vermilion […]

Study links breast cancer to the body’s internal clock

09.05.2018 Health Problems

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer. But researchers at Texas A&M University have now identified another gene that may have an impact on breast cancer—associated with the body’s circadian rhythm. Texas A&M College of Veterinary Medicine & Biomedical Sciences (CVM) professor Weston Porter and his team have found […]

Study discovers new molecular mechanism likely involved in cancer metastasis

08.05.2018 Health Problems

Cancer is most devastating when it metastasizes—when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor. A significant amount of scientific research has focused on finding ways to prevent metastasis. For some time, scientists have understood that a particular biochemical pathway, known as the PDK1 pathway, is active in metastasizing cancer cells. […]

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