Scientists develop novel drug that could potentially treat liver cancer more effectively

A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma (HCC), or primary liver cancer. This landmark discovery opens the door for more effective treatment of liver cancer with less side effects. […]

Continue reading »

Blocking digestive hormone may prevent diet-induced pancreatic cancer

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases). The new findings are published ahead of print in the American Journal of Physiology—Gastrointestinal and […]

Continue reading »

Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina (MUSC) and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes. Tumor suppressors act like brakes that stop cells from undergoing uncontrolled […]

Continue reading »

Liver cancer cell ‘switch’ found that could improve future therapies

Imperial researchers have found a new cell mechanism that could be used to target tumours in the future. The newly discovered ‘switch’ controls the activity of two proteins – ‘deleted in liver cancer-1’ (DLC1), a tumour suppressor, and talin. Both proteins control whether or not cancer cells spread to other parts of the body, but the exact mechanisms have remained […]

Continue reading »

New strategy for cancer therapy spells double trouble for tumors

Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects. The study, published recently in Nature Communications, shows that a molecule in cells, called Rad52, repairs special kinds of damaged DNA that accumulate in […]

Continue reading »

Large US study targets prostate cancer in black men

(HealthDay)—Black men in the United States have higher rates of aggressive prostate cancer than other males. Now, a $26.5 million study is underway to figure out why. The U.S. National Institutes of Health and the Prostate Cancer Foundation have launched the study to investigate social, environmental and genetic factors behind this disparity. “No group in the world is hit harder […]

Continue reading »

Greater efforts are needed to address ‘financial toxicity’ of cancer treatment

In addition to facing new concerns about their health, individuals who are diagnosed with cancer often worry about the financial burdens of treatment. A new study indicates that many patients feel that such ‘financial toxicity’ is not adequately addressed by their doctors and other clinicians. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer […]

Continue reading »

Low/no calorie soft drinks linked to improved outcomes in advanced colon cancer patients

Drinking artificially-sweetened beverages is associated with a significantly lower risk of colon cancer recurrence and cancer death, a team of investigators led by a Yale Cancer Center scientist has found. The study was published today in the journal PLOS ONE. “Artificially sweetened drinks have a checkered reputation in the public because of purported health risks that have never really been […]

Continue reading »

The cause of prostate cancer progression to the incurable stage has likely been uncovered

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. The study is published in the journal Cell. Three billion base pairs […]

Continue reading »
1 14 15 16 17 18 26