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It is encouraging to see greater attention in the media to the issue of climate change and its effects on the life-support systems of the planet. The link between breast cancer and the environment, however, is being overlooked. Premenopausal women exposed to high levels of air pollution have a 30 per cent increased risk for breast cancer, according to a […]
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According to the National Cancer Institute, patients diagnosed with non-small cell lung cancer (NSCLC) between the years 1995 and 2001 had 15 percent chance of being alive 5 years later. For patients with stage IV disease, describing cancer that has spread to distant sites beyond the original tumor, that statistic drops to 2 percent. Now a University of Colorado Cancer […]
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Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products (AGEs) could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective. AGE accumulation is the natural and unavoidable result of […]
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Gemcitabine given in combination with nab-paclitaxel is the standard of care for patients with advanced pancreatic cancer. This practice, however, rests on data obtained from several recent clinical trials enrolling patients with pancreatic cancer who skewed younger and in better overall condition than most. Currently, there is limited data regarding the management of patients who are older and in worse […]
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An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain. The guideline, released by the Canadian Task Force on Preventive Health Care, is published in CMAJ (Canadian Medical Association Journal). Based on the latest […]
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While other toddlers her age were fighting naptime, two-year-old Michelle was battling an aggressive, life-threatening cancer. Doctors at Children’s Hospital Los Angeles saved her life in an epic battle, wielding what is being hailed as a “magic bullet” in the fight against certain cancers. CHLA’s Leo Mascarenhas, MD, MS, saw promise in larotrectinib when he helped design the clinical trial […]
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The most comprehensive genome-wide association study, or GWAS, of colorectal cancer risk to date, published today in Nature Genetics, has discovered 40 new genetic variants and validated 55 previously identified variants that signal an increased risk of colon cancer. The study, led by a team of investigators at Fred Hutchinson Cancer Research Center, also has identified the first rare protective […]
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Small cell lung cancer (SCLC) represents up to 25 percent of lung cancer cell deaths and is associated with early metastasis and poor patient survival. Thus, SCLC is in need of better therapeutics and more efficient targeted treatments. Jonathan Lehman, MD, PhD, Pierre Massion, MD,and colleagues have demonstrated that somatostatin receptor 2 (SSTR2), considered to be a cell growth inhibitor, […]
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It can take up to a year for some bowel cancer patients in the UK to start treatment, according to international research co-ordinated by Cancer Research UK and published in the BMJ Open today. Researchers found that it took a year or more from first spotting a symptom to beginning treatment for 10% of patients in England, Northern Ireland and […]
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The most popular YouTube videos on prostate cancer often offer misleading or biased medical information that poses potential health risks to patients, an analysis of the social media platform shows. Led by researchers at NYU School of Medicine and its Perlmutter Cancer Center, the study of the 150 most-viewed YouTube videos on the disease found that 77 percent had factual […]
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