Autism-related genetic mutations occur in aging brains of Alzheimer’s patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy. Activity-dependent neuroprotective protein (ADNP) is a dominant gene whose de novo (during pregnancy) mutations are known to cause autism-related intellectual disabilities. A new Tel Aviv University study has found that ADNP mutations continue to occur in old age and accumulate in […]

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Untangling the brain’s life-support network

The portion of the brain known as the hypothalamus is small but mighty—it controls fundamental behaviors and physiology that are essential for survival. These include eating and drinking, sexual and defensive behaviors, sleep, and physiological control of things like body temperature, fluid balance, and the body’s responses to stress. A USC Dornsife-led study, published in the Proceedings of the National […]

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How brains distinguish between self-touch and touch by others

The brain seems to reduce sensory perception from an area of skin when we touch it ourselves, according to a new study from Linköping University published in the journal Proceedings of the National Academy of Sciences. The finding increases the understanding of how the brain distinguishes between being touched by another person and self-touch. The ability to distinguish between self […]

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To detect new odors, fruit fly brains improve on a well-known computer algorithm

It might seem like fruit flies would have nothing in common with computers, but new research from the Salk Institute reveals that the two identify novel information in similar ways. The work, which appeared in Proceedings of the National Academy of Sciences (PNAS) on December 3, 2018, not only sheds light on an important neurobiological problem—how organisms detect new odors—but […]

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Science Says: How family separation may affect kids’ brains

Doctors have long known that separating families and other traumatic events can damage children’s well-being. More recent research has shed some light on how that may happen: Severe early adversity may cause brain changes and “toxic stress,” resulting in lasting psychological and physical health problems. A “zero-tolerance” immigration policy announced this spring by the Trump Administration has separated 2,300 children […]

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Study identifies protein’s role in mediating brain’s response to stress

A study led by Massachusetts General Hospital (MGH) investigators has identified a critical role for a protein called Kruppel-like factor 9 (Klf9) in the brain’s response to stress, which has implications for protecting against the effects of stress in conditions like major depression and post-traumatic stress disorder (PTSD). In their paper published in Cell Reports, the team describes finding that […]

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