Blood vessels instruct brain development

Function and homeostasis of the brain relies on communication between its complex network of cells. Consequently, development of the different groups of cells in the brain needs to be coordinated in time and space. The group of Amparo Acker-Palmer (Buchmann Institute of Molecular Life Sciences and the Institute of Cell Biology and Neuroscience, Goethe University) reported in the last issue […]

Continue reading »

Automated detection of focal epileptic seizures in a sentinel area of the human brain

Patients with focal epilepsy that does not respond to medications badly need alternative treatments. In a first-in-humans pilot study, researchers at the University of Alabama at Birmingham have identified a sentinel area of the brain that may give an early warning before clinical seizure manifestations appear. They have also validated an algorithm that can automatically detect that early warning. These […]

Continue reading »

Scientists tie specific brain circuit to sociability in mice

Social behavior in mouse models of autism spectrum disorder normalized when investigators triggered the release of a specific signaling substance, serotonin, in a single part of the animals’ brains, according to a study from the Stanford University School of Medicine. “This points to a previously understudied brain mechanism that contributes to an inability to derive pleasure from social interactions,” said […]

Continue reading »

A video game can change the brain, may improve empathy in middle schoolers

A space-exploring robot crashes on a distant planet. In order to gather the pieces of its damaged spaceship, it needs to build emotional rapport with the local alien inhabitants. The aliens speak a different language but their facial expressions are remarkably humanlike. This fantastical scenario is the premise of a video game developed for middle schoolers by University of Wisconsin–Madison […]

Continue reading »

pH imbalance in brain cells may contribute to Alzheimer’s disease

Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer’s disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells. Astrocytes work to clear so-called amyloid beta proteins from the spaces between neurons, but decades of evidence has shown […]

Continue reading »

Traumatic brain injury: Discovery of two molecules could lead to new drug treatments

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments. The molecules promote full recovery after traumatic brain injury (TBI) in mice, according to the study published online in Neurobiology of Disease. Traumatic brain injury is the leading cause of […]

Continue reading »

New diagnostic blood test helps rule out need for CT scans in some patients with possible traumatic brain injuries

Research conducted at the Wayne State University School of Medicine has helped confirm the effectiveness of a blood biomarker that can indicate if patients with a head injury can avoid a costly CT scan because the blood test results indicate no traumatic brain injury (TBI). The findings, published online in The Lancet Neurology on July 24, validated the use of […]

Continue reading »
1 7 8 9 10 11 16