New study finds evidence of brain injuries in football players at surprisingly young age

There have been more and more cases confirming that repeated hits to the head have lifelong consequences for professional football players, but a new study by Orlando Health in collaboration with the Concussion Neuroimaging Consortium finds evidence of lasting effects from head injuries at a much younger age than expected. The study tested biomarkers in the blood called microRNA’s and […]

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Heart health’s impact on brain may begin in childhood

A child’s blood pressure could indicate cognition problems into adulthood, according to a new study suggesting the cardiovascular connection to cognitive decline could begin much earlier in life than previously believed. The findings may provide a window into the roots of dementia, for which high blood pressure is considered a risk factor. “We wondered is there perhaps some signal early […]

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The reward system in the brain affects our judgments

We make judgements quite rationally or “by the gut.” Not only experience and relevant information play an important role, but also our preferences. A study by the Max Planck Institute for Metabolism Research in Cologne shows how the reward system in the brain conveys judgements affected by one’s own desires. “In complex, confusing situations, we run the risk of making […]

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Research shows signalling mechanism in the brain shapes social aggression

Duke-NUS researchers have discovered that a growth factor protein, called brain-derived neurotrophic factor (BDNF), and its receptor, tropomyosin receptor kinase B (TrkB) affects social dominance in mice. The research has implications for understanding the neurobiology of aggression and bullying. “Humans and rodents are social animals. Our every interaction follows rules according to a social hierarchy. Failure to navigate this hierarchy […]

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Fat fuels aggressive brain cancers

Fat is powering tumour growth in brain cancer, finds a new study by Cardiff University and the University of Florida. Investigating the different types of cells in glioblastoma, the research team have gained a valuable insight into what fuels slow and fast dividing cancer cells, unveiling the potential to target aggressive brain cancer more effectively. Dr. Florian Siebzehnrubl, European Cancer […]

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Scientists uncover how rare gene mutation affects brain development and memory

Researchers from the University of California, Irvine School of Medicine, have found that a rare gene mutation alters brain development in mice, impairing memory and disrupting the communication between nerve cells. They also show memory problems could be improved by transplanting a specific type of nerve cell into the brain. The findings were published today in Neuron. “Mutations in hundreds […]

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Abnormal vision in childhood can affect brain functions

A research team has discovered that abnormal vision in childhood can affect the development of higher-level brain areas responsible for things such as attention. The researchers from the University of Waterloo, University of British Columbia, and the University of Auckland uncovered differences in how the brain processes visual information in patients with various types of lazy eye. In doing so, […]

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Study holds promise for new pediatric brain tumor treatment

New research published in Nature Communications from scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Stanford University School of Medicine, shows a specific protein regulates both the initiation of cancer spreading and the self-renewal of cancer cells in medulloblastoma, a type of pediatric brain cancer. Among children’s cancers, brain cancer […]

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Cancer patients with rare deadly brain infection treated successfully with off-the-shelf adoptive T-cell therapy

An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection sometimes observed in patients with cancer and other diseases in which the immune system is compromised. The study, led by Katy Rezvani, M.D., Ph.D., professor, Department of Stem Cell Transplantation […]

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Cells in ‘little brain’ have distinctive metabolic needs

Cells’ metabolic needs are not uniform across the brain, researchers have learned. “Knocking out” an enzyme that regulates mitochondria, cells’ miniature power plants, specifically blocks the development of the mouse cerebellum more than the rest of the brain. The results are scheduled for publication in Science Advances. “This finding will be tremendously helpful in understanding the molecular mechanisms underlying developmental […]

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