Obesity may hasten disability in patients with rheumatoid arthritis

In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a […]

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How environmental pollutants and genetics work together in rheumatoid arthritis

It has been known for more than three decades that individuals with a particular version of a gene—human leukocyte antigen (HLA)—have an increased risk for rheumatoid arthritis. Meanwhile, in recent years, there has been a growing interest in the relationship between rheumatoid arthritis and environmental factors, such as cigarette smoking. In smokers who develop rheumatoid arthritis, the disease hits harder. […]

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Flare-responsive hydrogel developed to treat arthritis

Arthritis flares – the unpredictable and often sudden worsening of arthritis symptoms—can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians. But investigators at Brigham and Women’s Hospital have found that flares may also represent an important opportunity for improving treatment options for patients. In experiments […]

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