Chikungunya antibody set to enter clinical trial

A monoclonal antibody against the chikungunya virus developed by researchers at Vanderbilt University Medical Center is the first monoclonal antibody encoded by messenger RNA to enter a clinical trial. Moderna Inc., a biotechnology firm based in Cambridge, Massachusetts, that is focused on developing mRNA-based vaccines and therapeutics, announced the clinical trial earlier this month. The specific antibody against the mosquito-borne […]

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Antibody ‘cocktail’ can prevent Zika infection but is not effective for treatment of fetuses

A “cocktail” of monoclonal antibodies that can prevent Zika virus (ZIKV) infection in primates was not effective for treatment of fetuses, according to a new collaborative study led by a University of Miami Miller School of Medicine research team. “We observed that ZIKV isolated from pregnant women in Rio de Janeiro also causes fetal infection in pregnant macaques. Unfortunately, we […]

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