Biochemist, physicist team to see antibacterial TCS deform mitochondria

Grocery shopping can be an illuminating chore for a toxicologist. Julie Gosse, a University of Maine associate professor of molecular and biomedical sciences, has scanned the supermarket aisles for products that contain triclosan (TCS), a synthetic antibacterial agent. Since the ’90s, TCS has been in a slew of consumer products, including facial cleansers, toothpaste, mouthwash and hand sanitizers. For years, […]

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Antibacterial in your toothpaste may combat severe lung disease

A common antibacterial substance found in toothpaste may combat life-threatening diseases such as cystic fibrosis, or CF, when combined with an already FDA-approved drug. Michigan State University researchers have found that when triclosan, a substance that reduces or prevents bacteria from growing, is combined with an antibiotic called tobramycin, it kills the cells that protect the CF bacteria, known as […]

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Researchers define target and mechanism of antibacterial drug fidaxomicin (Dificid)

A team of Rutgers University and international scientists has determined the molecular target and mechanism of the antibacterial drug fidaxomicin (trade name Dificid). Fidaxomicin was approved in 2011 for treatment of the CDC “urgent threat” bacterial pathogen Clostridium difficile (C. diff) and currently is one of two front-line drugs for treatment of C. diff. Fidaxomicin also exhibits potent antibacterial activity […]

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