Researchers develop method for identifying aggressive breast cancer drivers

Precision cancer medicine requires personalized biomarkers to identify patients who will benefit from specific cancer therapies. In an effort to improve the accuracy of predictions about prognosis for patients with breast cancer and the efficacy of personalized therapy, University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a method to precisely identify individual patients who have aggressive breast […]

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More aggressive statin tx needed after heart attack in young patients

(HealthDay)—The majority of young heart attack patients with familial hypercholesterolemia (FH) still have elevated cholesterol levels a year later, according to a study published in the May 21 issue of the Journal of the American College of Cardiology. Avinainder Singh, M.D., from Brigham and Women’s Hospital in Boston, and colleagues used data from the YOUNG-MI registry to assess the prevalence […]

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New nanomedicines for a more efficient and less aggressive treatment of prostate cancer

In Europe, prostate cancer is the most common type of cancer among men with an incidence greater than 100 cases per 100,000 individuals. Furthermore, it is currently the second most common cause of cancer-related deaths among men. This pathology mainly affects elderly men: nine in 10 deaths take place after 65 years of age. Therefore, it represents a very serious […]

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Aggressive behavior brings emotional pain to the sadist

People with sadistic personality traits tend to be aggressive, but only enjoy their aggressive acts if it harms their victims. According to a series of studies of over 2000 people, these actions ultimately leave sadists feeling worse than they felt before their aggressive act. The research appears in Personality and Social Psychology Bulletin, published by the Society for Personality and […]

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Fat fuels aggressive brain cancers

Fat is powering tumour growth in brain cancer, finds a new study by Cardiff University and the University of Florida. Investigating the different types of cells in glioblastoma, the research team have gained a valuable insight into what fuels slow and fast dividing cancer cells, unveiling the potential to target aggressive brain cancer more effectively. Dr. Florian Siebzehnrubl, European Cancer […]

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Media violence, impulsivity and family conflict tied to aggressive behaviors in teenagers

Teenagers exposed to TV and film violence and high levels of household conflict are at risk of engaging in aggressive behaviors, according to a new study by researchers at three U.S. universities. Especially prone to aggressive tendencies are those who also have high levels of impulsivity, the six-member research team reported in a study published online ahead of print in […]

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Researchers find adult stem cell characteristics in aggressive cancers from different tissues

UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues—which line all of the organs and cavities inside the body—and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a […]

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Dying cancer cells make remaining glioblastoma cells more aggressive and therapy-resistant

A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy. Paradoxically, the sending cells in this signaling are glioblastoma cells that are undergoing programmed cell death, or apoptosis, according to research by a team at institutes in the United States, Russia and South Korea. The dying cancer […]

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