Effective drug delivery to heart with tannic acid

Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones. To efficiently treat cardiovascular and related vascular diseases without surgery, a KAIST research team developed a heart-targeting drug delivery technology using tannin acid via intravenous systemic injection. This method can be applied to the development of a variety of new protein-based […]

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Dexmedetomidine cuts γ-aminobutyric acid receptor function

(HealthDay)—Dexmedetomidine prevents excessive γ-aminobutyric acid type A receptor function after anesthesia, according to a study published online June 7 in Anesthesiology. Dian-Shi Wang, M.D., Ph.D., from the University of Toronto, and colleagues studied injectable and inhaled anesthetic drugs (etomidate and sevoflurane) using cultured murine hippocampal neurons, cultured murine and human cortical astrocytes, and ex vivo murine hippocampal slices. Using electrophysiologic […]

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Sulfur amino acid restriction could amount to new dietary approach to health

The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to Penn State College of Medicine researchers who recently conducted a review of published studies. More research is needed to confirm the benefits in people, the scientists said. Amino acids are the building blocks of all proteins in the body. A subcategory […]

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