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Gene therapy has shown promise in treating inherited genetic diseases, but a major issue that has frustrated scientists remains: Replacing a “bad” gene with a healthy one often is a short-lived fix. Typically, the healthy replacement gene works for just a few weeks. Now, scientists at Washington University School of Medicine in St. Louis have combined the gene-editing tool CRISPR […]
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Sirolimus, which is used to prevent rejection after kidney transplants, has been used to successfully treat three cases of a rare disorder called diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, or DIPNECH syndrome. The syndrome is so rare that there are no clinical recommendations to guide care and, therefore, no proven therapies. The brief case report is published in Annals of […]
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Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome – a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness, the circadian clock exerts control […]
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For patients with difficult-to-treat, drug-resistant infections, seeing an infectious diseases specialist can be a lifesaver. Such patients experienced significantly lower mortality rates when treated by physicians specializing in infectious diseases, according to a study at Washington University School of Medicine in St. Louis. Researchers found that infectious disease physicians helped reduce 30-day mortality rates by more than a half, and […]
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More than 70 years since the end of World War II, there are still signs of intergenerational transmission of Holocaust trauma that are manifested in the way adult offspring of Holocaust survivors care for their elderly parents, according to a new study by researchers at Bar-Ilan University. To this day scholars debate whether intergenerational transmission of Holocaust trauma indeed exists. […]
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Matching unique genetic information from cancer patients’ tumors with treatment options – an emerging area of precision medicine efforts – often fails to identify all patients who may respond to certain therapies. Other molecular information from patients may reveal these so-called “hidden responders,” according to a Penn Medicine study in Cell Reports this week. The findings are published alongside several […]
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Research led by a psychologist at the University of California, Riverside, shows that bilinguals regulate, or suppress, their native language when reading in a second language. Many in media and in science often assume that reading or speaking in a second language—one that has been learned later in life than the native or first language—is always going to be difficult. […]
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(HealthDay)—Parents who read to their infants and toddlers may help them develop skills that pay big dividends when they start school, a new study suggests. Specifically, reading aloud and pretend play may offset disruptive behaviors—such as hyperactivity and aggression—and improve attention, researchers found. “When you read with your child, it’s really a warm, nice time together,” said lead researcher Dr. […]
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Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome – a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness, the circadian clock exerts control […]
Continue reading »
Controlling blood pressure with any of the commonly prescribed antihypertensive medications can prevent dementia in older African-Americans with hypertension according to a new study from Regenstrief Institute researchers. African Americans are especially at risk of both hypertension and dementia. The new study provides substantial evidence of significant reduction of risk of onset of dementia for African American men and women […]
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