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In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute myeloid leukemia (AML) and describe how the drug works at the molecular level. The findings have led to a Phase I/II clinical trial for patients with advanced AML and […]
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For the first time, the history charting the world-renowned Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the ’90s, back to its beginnings has been made accessible. The work, made possible thanks to a Wellcome grant and a dedicated team of archivists from the University’s Special Collections, will mean that researchers can now access the […]
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Beta blockers have become a prescription drug staple for recovering heart attack patients. However, these blood pressure-reducing medications cannot be tolerated by many patients who are at higher risk for developing cardiovascular disease, including those with chronic obstructive pulmonary disease (COPD) and asthma, the elderly, and diabetics. As seen in the March 26 issue of Thyroid, researchers at New York […]
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Searching the entire genome, a Yale research team has identified a gene that when eliminated can spur regeneration of axons in nerve cells severed by spinal cord injury. “For the first time, the limits on nerve fiber regeneration were studied in an unbiased way across nearly all genes,” said Stephen Strittmatter, the Vincent Coates Professor of Neurology and senior author […]
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The child welfare system is more likely to intervene in households in “less neighborly” neighborhoods and in which parents spank their kids, a new study shows. Researchers at the University of Michigan and Michigan State University conducted analyses on nearly 2,300 families from 20 large U.S. cities who responded to surveys and interviews. Participating families had a child who was […]
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Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies. The drug may not become available to patients for a number of years yet, but researchers believe that if clinical trials are successful, it could be used to tackle a variety of treatment-resistant cancers. Patients with breast […]
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University of Queensland researchers have developed a vaccine delivery technology that enables treatment to be tailored precisely for different cancers. UQ’s Professor Ranjeny Thomas said the technology had the potential to improve the precision of cancer immunotherapy, leading to better cancer outcomes and reduce harmful side-effects. “Flexible cancer vaccines are a long-sought treatment strategy in cancer immunotherapy,” Professor Thomas said. […]
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Even one night of lost sleep may cause the brain to fill with protein chunks that have long been linked to the development of Alzheimer’s disease, a new study warns. People deprived of sleep for one night experience an immediate and significant increase in beta amyloid, a substance that clumps together between neurons to form plaques that hamper the brain’s […]
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Government and other scientists are proposing a new way to define Alzheimer’s disease—basing it on biological signs, such as brain changes, rather than memory loss and other symptoms of dementia that are used today. The move is aimed at improving research, by using more objective criteria like brain scans to pick patients for studies and enroll them sooner in the […]
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A new study by Althea Campuzano, Ph.D. a student at The University of Texas at San Antonio, and Floyd Wormley, Jr., Professor of Biology and Senior Associate Dean for Research and Graduate Studies, sheds light on little-known fungal infections caused by the fungus Cryptococcus. There are currently no vaccines available for any fungal infection, which can be extremely deadly to […]
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