Family Medicine News

New tools to boost the delivery of drugs to cancer tumours

02.05.2018 Health Problems

The treatment of cancer tumours is made complex by their microenvironment and the abnormalities of the blood vessels sustaining them. The EU-funded NeoNaNo project has developed methods to improve drug delivery to tumours and improve the efficacy of anticancer therapy. Drug delivery to tumours is difficult. The blood vessels they depend on are abnormally structured, heterogeneously distributed and relatively poorly […]

Virtual drug trials boost results

02.05.2018 Health Problems

Bringing a new drug to market can cost more than two billion dollars. Not to mention years of work spent developing and testing for scientists, researchers, doctors, and trial participants. By bringing trials to the virtual realm, Belinda H. Tan ’96 has found a way to cut all that in half. Her company, Science 37, is moving the entire drug […]

Infants exposed to hepatitis C increasing, yet not adequately screened, study finds

02.05.2018 Health Problems

Due to the opioid epidemic, hepatitis C virus (HCV) is increasingamong pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children. Despite this increased prevalence, HCV-exposed infants are not adequately screened and many pediatric HCV infections remain undetected, according to a new study from researchers at Magee-Womens Research Institute (MWRI). The results are reported in […]

Study shows why bosses cut some employees slack for unethical behavior

02.05.2018 Health Problems

Imagine—or perhaps you don’t have to—that you’re at work and feeling very tired. You’re nearing the deadline on an important project, and you’ve stayed late at the office every day for weeks. Perhaps because you’re feeling so fatigued, when you submit an expense report for a recent lunch, you may round up just a smidge. Now imagine you are the […]

Brick by brick—assembly of the measles virus

02.05.2018 Health Problems

Researchers have been able to capture images of measles viruses as they emerge from infected cells, using state of the art cryo-electron tomography techniques. The new images will help with a greater understanding of measles and related viruses, and could give hints on antiviral drug strategies likely to work across multiple viruses of this type. The results were published Monday, […]

FDA approves CAR T therapy for large B-cell lymphoma

02.05.2018 Health Problems

The U.S. Food and Drug Administration (FDA) has expanded approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adult patients with relapsed or refractory large B-Cell lymphoma after two or more lines of systemic therapy. Today’s approval includes treatment of diffuse large B-cell lymphoma (DLBCL) – the most […]

Formate prevents most folic acid-resistant neural tube defects in mice

02.05.2018 Health Problems

Maternal folic acid supplementation has reduced the prevalence of neural tube defects, one of the most common structural malformations in people, by up to 80 percent. However, many infants are still born with a neural tube defect that appears to be resistant to folic acid supplementation. In this study, a multi-institutional research team has developed a novel folic acid-resistant neural […]

To improve future relationship with your kids, turn up the music

02.05.2018 Health Problems

If you’re a parent whose teenagers spend family road trips with earbuds firmly in place, you may want to encourage them to unplug, then turn the car radio to something the whole family can enjoy. It just might do wonders for your future relationship with your son or daughter, according to a new study from the University of Arizona. Researchers […]

Scientists identify two hormones that burn fat faster, prevent and reverse diabetes in mice

02.05.2018 Health Problems

UCLA geneticists have created a new technique to hunt for hormones that influence how organs and tissues communicate with each other. The method enabled them to find naturally occurring molecules that play major roles in Type 2 diabetes, obesity and cardiovascular disease. In particular, they discovered: Two hormones called “notum” and “lipocalin-5” that speed up the body’s ability to burn […]

New lab study reveals how breast cancer drug can accelerate cancer cell growth

01.05.2018 Health Problems

The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab, according to a new study published in eLife. By understanding the molecular basis of this phenomenon, scientists hope that their findings will lead to safer treatment decision-making and drug design in the future. Lapatinib is used in combination with other […]

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