Family Medicine News

Common diabetes drug found safe for most diabetics with kidney disease

05.06.2018 Health Problems

Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin’s association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function. […]

Researchers discover how colon cancer mutates to escape the immune system

05.06.2018 Health Problems

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process. This ability of cancer to change its genes—a process called immunoediting—had never been described in colon cancer before, and the new understanding could help researchers develop new immunotherapies that target […]

Increased follow-up does not benefit colorectal cancer patients

05.06.2018 Health Problems

Logically, it would seem that more follow-up testing of cancer patients must be better—but this is not the case for patients who undergo surgery for colorectal cancer. This is an important conclusion from a study in which 2,509 patients with colorectal cancer were offered two and five follow-up tests in the form of CT scans combined with a blood test […]

Newly identified genetic markers classify previously undetermined glioblastoma tumors

05.06.2018 Health Problems

Most glioblastoma tumors are marked by one or two broad mutation patterns, but about 20 percent of the lethal brain tumors have biomarkers that cannot be identified. Now scientists at Duke Cancer Institute have identified mutations for the vast majority of the remaining 20 percent of uncharacterized tumors, which tend to be especially lethal. The findings indicate that these mutations […]

The Cure for Cancer Might Just Be in Your Own Cells

05.06.2018 Family Health

Tori Lee was diagnosed with Acute Lymphoblastic Leukaemia (ALL), a blood cancer of very a aggressive form, when she started kindergarten in 2008. Immediately after the horrifying news, she started chemotherapy. Sadly, the chemo didn’t work, and the cancer persisted. According to her mother, Dana Lee, Tori underwent chemotherapy for almost two years before relapsing to the cancer after which they signed […]

Extended chemo extends life for children with rare cancer

05.06.2018 Health Problems

(HealthDay)—Children suffering from rhabdomyosarcoma, a rare cancer of the muscle tissue, may have better chances for a cure if they have extended chemotherapy, a new study finds. In a phase 3 clinical trial, adding six months of low-dose maintenance chemotherapy after initial treatment extended the five-year survival rate from 74 percent to 87 percent, researchers found. Children with rhabdomyosarcoma who’ve […]

Checkpoint inhibitor shrinks advanced squamous cell skin cancer

05.06.2018 Health Problems

Clinical trials show that an immune checkpoint inhibitor shrinks the tumors of nearly half of patients with an incurable, advanced form of a common skin cancer, an international team led by a researcher at The University of Texas MD Anderson Cancer Center reports in the New England Journal of Medicine. “These results mark a potential paradigm shift in the treatment […]

Study finds rare gain for tough-to-treat pancreatic cancer

04.06.2018 Health Problems

Patients with pancreatic cancer that hadn’t spread lived substantially longer on a four-drug combo than on a single standard cancer drug, a rare advance for a tough-to-treat disease, researchers reported Monday. The results indicate the powerful chemotherapy treatment known as folfirinox will likely become standard of care for the minority of patients whose pancreatic cancer is diagnosed early enough to […]

No new adverse events reported for DTaP vaccination

04.06.2018 Kids Health

(HealthDay)—No new or unexpected safety issues have been identified in association with diphtheria-tetanus-acellular pertussis (DTaP) vaccines in the United States, according to a study published online June 4 in Pediatrics. Pedro L. Moro, M.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues searched the Vaccine Adverse Event Reporting System (VAERS) for U.S. reports of […]

New study points to a potential ‘Achilles heel’ in brain cancer

04.06.2018 Health Problems

Scientists at Virginia Commonwealth University believe they have uncovered an “Achilles heel” of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer. Their study published this week in the Proceedings of the National Academy of Sciences details how a mechanism that protects glioma stem cells can potentially be exploited to develop new and more effective treatments for […]

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