Study evaluates efficacy and safety of pancreatic cancer treatment in complex patient care cases

Gemcitabine given in combination with nab-paclitaxel is the standard of care for patients with advanced pancreatic cancer. This practice, however, rests on data obtained from several recent clinical trials enrolling patients with pancreatic cancer who skewed younger and in better overall condition than most. Currently, there is limited data regarding the management of patients who are older and in worse […]

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New light-based technology reveals how cells communicate in human disease

Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each other by releasing signalling molecules; this helps to ensure that tissues function normally, that the immune system is able to respond to infection, and that cell division and survival […]

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Breast cancer screening: New emphasis on shared decision-making between women and their doctors

An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain. The guideline, released by the Canadian Task Force on Preventive Health Care, is published in CMAJ (Canadian Medical Association Journal). Based on the latest […]

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DF-PGT, now possible through massive sequencing techniques

A research team from the Universitat Autònoma de Barcelona (UAB), in collaboration with the Blood and Tissue Bank of Catalonia, has implemented a massive sequencing platform for preimplantation genetic testing (PGT) for the first time in history. The work adapts the TruSight One (TSO) platform, one of today’s most complete genetic panels, to Double Factor Preimplantation Genetic Testing (DF-PGT). The […]

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Tissue stiffness is a

Imagine being at a packed concert hall with a mosh pit full of dancers creating a wall against outsiders. When targeted drugs try to make their way toward a pancreas tumor, they encounter a similar obstacle in stiff tissue that surrounds and protects the cancer. A new University of Rochester study demonstrates how imaging technology can be used to accurately […]

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How parents and teachers can identify and help young people self-medicating trauma with drugs and alcohol

Some 80% of young people will experience a traumatic event by the time they become an adult. Rates of exposure to trauma peak during adolescence. The stress from traumatic events can result in a loss of interest in school, friends, hobbies, and life in general. The types of traumatic events include a wide range of terrifying and life-threatening experiences such […]

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Kids benefit when parents overcome math anxiety

Parents who are anxious about math can still help their children learn the subject when given the right tools, according to research from current and former University of Chicago scholars. A new study published in the December issue of the Journal of Experimental Psychology found that math-anxious parents who used an app called Bedtime Math saw improvement in their children’s […]

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Are near-death experiences hallucinations? Experts explain the science behind this puzzling phenomenon

In our never-ending quest to understand what happens to us after we die, humans have long seen the rare phenomenon of near-death experiences as providing some hints. People who’ve had a brush with death often report seeing and experiencing life-altering events on “the other side,” like a bright white light at the end of a long tunnel, or being reunited […]

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PPIs combined with oral anticoagulants reduce risk of gastrointestinal bleeding

A Vanderbilt University Medical Center (VUMC) study published today in JAMA shows that patients already at higher risk for gastrointestinal bleeding gain a marked protection from this risk when they take a proton pump inhibitor (PPI) in combination with an oral anticoagulant. Oral anticoagulants, which prevent blood clot formation, are among the most widely prescribed medications in the United States. […]

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