New therapy approach points to potential treatment of liver cancer patients with hepatitis B virus infection

Researchers from Duke-NUS Medical School, Singapore General Hospital (SGH) and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma (HCC), a commonly occurring liver cancer. The treatment was also individualised, as T cells that were engineered were specific to the patients. The approach […]

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Researchers find targeting rare form of cystic fibrosis earlier prevents organ damage in ferrets

A team of researchers from the University of Iowa, University Medical Center Utrecht and Vertex Pharmaceuticals Incorporated, reports that earlier administration of a drug already given to patients with a rare form of cystic fibrosis can prevent organ damage—at least in ferrets. In their paper published in the journal Science Translational Medicine, the group describes their study of the impact […]

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Cannabis during pregnancy bumps psychosis risk in offspring

Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis. “Our research shows that prenatal marijuana exposure after maternal knowledge of pregnancy is associated with a small increase in psychosis proneness during middle childhood or about age 10,” said Jeremy Fine, an […]

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Newly single? How to beat the breakup blues

Whether you dated for weeks, months or years—when it ends, you can experience a range of emotions and feel a little uncertain about what’s next. Research even shows the pain from a breakup can activate pain receptors in our brain the same way that physical injuries do. When you’re feeling down and out, how do you beat the breakup blues? […]

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Untangling the brain’s life-support network

The portion of the brain known as the hypothalamus is small but mighty—it controls fundamental behaviors and physiology that are essential for survival. These include eating and drinking, sexual and defensive behaviors, sleep, and physiological control of things like body temperature, fluid balance, and the body’s responses to stress. A USC Dornsife-led study, published in the Proceedings of the National […]

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Scientists uncover novel strategy to target common type of cancer

Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife. The findings, originally posted on bioRxiv, suggest that targeting a protein called Werner syndrome helicase (WRN) could represent a novel opportunity for treating a subgroup of cancer patients with microsatellite instability-high (MSI-H) tumors. MSI is a […]

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Rineys give $15 million to develop, test therapies for neurodegenerative diseases

Washington University School of Medicine in St. Louis has received a $15 million gift from Paula and Rodger Riney aimed at accelerating research and developing new treatments for two major neurodegenerative diseases:  Alzheimer’s disease and Parkinson’s disease. Of the gift, $10 million will support Alzheimer’s disease research, while $5 million will support studies of Parkinson’s disease. The gift will help […]

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Probiotic bacteria evolve inside mice’s GI tracts

Probiotics – which are living bacteria taken to promote digestive health – can evolve once inside the body and have the potential to become less effective and sometimes even harmful, according to a new study from Washington University School of Medicine in St. Louis. Researchers studying a strain of Escherichia coli (E. coli) bacteria sold in Europe as an anti-diarrheal […]

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Aspiration noninferior to stent retriever for clot removal

(HealthDay)—Aspiration is as effective as the traditional stent retriever approach for clot removal in patients presenting with large-vessel occlusion stroke, according to a study published online March 9 in The Lancet. Aquilla S. Turk III, D.O., from Greenville Health System in South Carolina, and colleagues randomly assigned 270 patients presenting at 10 hospitals and four specialty clinics in the United […]

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