Health Problems Archives - Page 72 of 202

Loss of a DNA repair system creates a unique vulnerability in many cancer types

11.04.2019 Health Problems

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes’ activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies. Reporting in Nature, researchers led by members of the Cancer Dependency […]

Inhaled nanoparticles could treat lung cancer

10.04.2019 Health Problems

QUT pharmaceutical scientist Dr. Nazrul Islam, from School of Clinical Sciences, said lung cancer was one of the most common cancers globally and one of the deadliest, being a leading cause of cancer deaths. He said chitosan had long been investigated for drug delivery and medical applications. It is made from refined crustacean (prawns, crabs, lobster) shells and was an […]

Studies give new insights on immunotherapy in elderly patients with advanced NSCLC

10.04.2019 Health Problems

Two studies to be reported at ELCC 2019 provide new insights on the efficacy and safety of immunotherapy in elderly patients with advanced non-small-cell lung cancer (NSCLC), where information has previously been lacking despite being the age group most commonly affected. Immunotherapy with drugs that target immune pathways to enhance the body’s ability to recognise and destroy tumour cells is […]

A tiny cry for help from inside the liver could lead to better treatment

09.04.2019 Health Problems

On a normal day, the cells of a human liver do what they do best—making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile. But when something comes along that badly injures enough of those cells—such as a liver-damaging overdose of pain medicine—this vital work can come […]

Researchers develop treatment that turns tumors into cancer vaccine factories

08.04.2019 Health Problems

Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, injecting immune stimulants directly into a tumor to teach the immune system to destroy it and other tumor cells throughout the body. The “in situ vaccination” worked so well in patients with advanced-stage lymphoma that it is also undergoing trials in breast and head and neck cancer patients, […]

From spinal cord injury to recovery

08.04.2019 Health Problems

Spinal cord injury disconnects communication between the brain and the spinal cord, disrupting control over parts of the body. Studying the mechanisms of recovery, Leuven researcher Aya Takeoka (NERF) found that a specific type of neuronal feedback from sites below the injury plays a crucial role during early recovery and for maintaining regained motor functions. These new basic research findings […]

Screen time—even before bed—has little impact on teen well-being: study

05.04.2019 Health Problems

Data from more than 17,000 teenagers show little evidence of a relationship between screen time and well-being in adolescents. The study, published in Psychological Science, a journal of the Association for Psychological Science, casts doubt on the widely accepted notion that spending time online, gaming, or watching TV, especially before bedtime, can damage young people’s mental health. “Implementing best practice […]

High insulin costs come under fire on Capitol Hill

05.04.2019 Health Problems

(HealthDay)—For many Americans, the cost of lifesaving insulin is simply too high, leading as many as one in four to ration the drug, experts testifying before the House Committee on Energy and Commerce said this week. The meeting focused primarily on defining the problem and exploring potential solutions, such as lowering the list prices of insulin and increasing transparency so […]

Elucidation of functional mechanism of ‘love hormone,’ oxytocin, at molecular level

04.04.2019 Health Problems

Oxytocin is essential in activities of the social brain such as trust and love and in maternal bonding behaviors. It is produced in the brain and secreted into the circulation. Here, by analyzing maternal behaviors of RAGE gene-manipulated mice, oxytocin was found to be transported back to the brain, crossing the blood-brain barrier (BBB), an extremely effective barrier, by binding […]

Deep stimulation improves cognitive control by augmenting brain rhythms

04.04.2019 Health Problems

In a new study that could improve the therapeutic efficacy of deep-brain stimulation (DBS) for psychiatric disorders such as depression, a team of scientists shows that, when DBS is applied to a specific brain region, it improves patients’ cognitive control over their behavior by increasing the power of a specific low-frequency brain rhythm in their prefrontal cortex. The findings, published […]

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