Room for improvement in drug dosage timing in hospitals

Too many hospitals provide medications according to the practicalities of their staffing schedules rather than the ideal dosing times for their patients, according to a new study led by experts at Cincinnati Children’s. The study, published Oct. 1, 2019, in PNAS, was led by David Smith, MD, Ph.D., Divisions of Pediatric Otolaryngology and Pulmonary Medicine; Marc Ruben, Ph.D.; and John […]

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Mavyret approved as 8-week treatment for hep C, compensated cirrhosis

(HealthDay)—Approval of Mavyret (glecaprevir and pibrentasvir) tablets has been expanded to eight-week treatment for treatment-naive patients aged 12 years and older with chronic hepatitis C virus (HCV) genotypes 1 through 6 and compensated cirrhosis, the U.S. Food and Drug Administration announced last week. Mavyret is the first eight-week treatment approved for any treatment-naive HCV patients, regardless of cirrhosis status or […]

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Brestoff, Theunissen recognized by NIH for innovative research

Obesity expert Jonathan R. Brestoff, MD, PhD, and regenerative medicine specialist Thorold Theunissen, PhD, both of Washington University School of Medicine in St. Louis, have received High-Risk, High-Reward Research awards from the National Institutes of Health (NIH). The program supports scientists showing exceptional creativity and pursuing innovative research programs with the potential to have a wide impact in biomedical, behavioral […]

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Can herbicides cause breast cancer? Scientists discover a piece to the puzzle.

Scientists know that the solution to preventing breast cancer won’t come easily, but a collaborative team of scientists at Purdue University and the Institut National de la Santé et de la Recherche Médicale (INSERM)/Institut de Cancérologie de L’Ouest (ICO) in Nantes, France, say they’ve recently discovered one of the missing pieces of the puzzle when it comes to cancer prevention. […]

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How neural circuits form in a developing embryo

Neurons, take your places. The cells that eventually become neurons must first travel across the embryo to reach their final destinations in the nervous system. There, they blossom from undefined cells into neurons with specific roles, working together in circuits to direct an animal’s behavior. But exactly how this journey unfolds is still somewhat mysterious. “There are lots of things […]

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Study: Active voice conveys a sense of immediacy and increases the chance people will believe you

The way we interpret a message changes depending on whether it’s framed in the active or the passive voice, University of Toronto researchers have found—even if the content is exactly the same. “What we found is that depending on which form you choose, it changes how your audience comes to understand that message,” says Sam Maglio, an associate professor in […]

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Researchers developing new ‘DNA stitch’ to treat muscular dystrophy

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy (DMD). The treatment—a cocktail of DNA-like molecules—results in dramatic regrowth of a protein called dystrophin, which acts as a support beam to keep muscles strong. The protein is virtually absent […]

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