Health Problems Archives - Page 34 of 202

New treatment strategy may thwart deadly brain tumors

24.12.2019 Health Problems

Immune checkpoint inhibitors are important medications that boost the immune system’s response against certain cancers; however, they tend to be ineffective against glioblastoma, the most deadly primary brain tumor in adults. New research in mice led by investigators at Massachusetts General Hospital (MGH) and the University of Florida reveals a promising strategy that makes glioblastoma susceptible to these medications. The […]

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

23.12.2019 Health Problems

Anthracyclines remain a cornerstone of breast cancer therapy in combination with new-generation targeted drugs such as trastuzumab. Both types of drugs are major culprits in chemotherapy-induced heart disease. A recent study showed that being overweight or obese was a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer, but it did not take into account related cardiac risk factors […]

Researchers turn to Yelp reviews to learn how patients with addiction rate their treatment

23.12.2019 Health Problems

As the opioid crisis has worsened, addiction treatment programs have proliferated—but there’s no standardized way to rate those programs, researchers at the University of Pennsylvania note in a new study. So they turned to Yelp. The popular online review site is best-known for its restaurant ratings. But it’s also become a clearinghouse for people to rate just about anything—including addiction […]

Researchers identify neurons responsible for rapid eye movements/REM during sleep

20.12.2019 Health Problems

Rapid Eye Movement—not only the name of a successful American rock band, but also and not least a characteristic eye movement in paradoxical sleep, the stage with high dream activity. This sleep phase has a peculiarity: Although the muscle tone of the sleeping person is completely relaxed, the eyes suddenly move back and forth. The name “paradoxical sleep” is well […]

Researchers discover process that may explain how type 2 diabetes develops

20.12.2019 Health Problems

A new study helps to explain the mechanism by which pancreatic cells secrete high levels of insulin during the early stages of diabetes. A central question in diabetes research is why cells of the pancreas, known as beta cells, initially over-secrete insulin. The prevailing theory was that the body may be in the process of becoming “deaf” to insulin, so […]

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

20.12.2019 Health Problems

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types. Scientists at the Wellcome Sanger Institute and the Broad Institute of MIT and Harvard compared the consistency of the two datasets, independently verifying the methodology and findings. The […]

Artificial intelligence can now predict long-term risks of heart attack and cardiac death

19.12.2019 Health Problems

A new study in Cardiovascular Research finds that machine learning, the patterns and inferences computers use to learn to perform tasks, can predict the long-term risk of heart attack and cardiac death. Indeed, machine learning appears to be better at predicting heart attacks and cardiac deaths than the standard clinical risk assessment used by cardiologists. Researchers here studied subjects from […]

Type 1 diabetes: A new starting point to delay autoimmune response

19.12.2019 Health Problems

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective. Researchers at Helmholtz Zentrum München and LMU Munich have now deciphered a mechanism that impairs Treg differentiation and stability. In the study, when researchers inhibited the molecule that triggers this mechanism, an increased number of […]

Watermelon supplements bring health benefits to obese mice

19.12.2019 Health Problems

Eating watermelon in the form of powdered supplements helped adult obese mice avoid some detrimental health effects of an unhealthy diet, according to a new Oregon State University study. The study is published in the Journal of Nutrition. A significant next step in this research would be a human clinical trial, said study co-author Neil Shay, professor of food science […]

Here’s what happens in the brain when we disagree

19.12.2019 Health Problems

We’ve all been there. You are in the middle of a heated disagreement when you lose respect for the opposing party. Whether it is about the latest election or childcare, you feel like your considered arguments are not appreciated—perhaps even ignored. But did you ever wonder what exactly is happening in the mind of the person on the other side? […]

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