A hydrogel restores breathing after spinal cord injury in animal models

One of the most severe outcomes of spinal cord injury from car accidents, sports impacts, or other neck trauma, is losing the ability to control breathing, with patients often requiring artificial ventilation for the rest of their lives. Researchers at Jefferson (Philadelphia University + Thomas Jefferson University) recently tested a hydrogel that releases a nerve-protecting agent at the site of […]

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D-transposition of the great arteries—a new era in cardiology

In the current issue of Cardiovascular Innovations and Applications , Angeline D. Opina and Wayne J. Franklin from the Baylor College of Medicine and Texas Children’s Hospital, Houston, TX, USA consider the D-transposition of the great arteries. D-transposition of the great arteries (d-TGA) is the second most common cyanotic congenital heart disease (CHD) lesion, accounting for 3-5% of all CHD, […]

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Virtual brain gives insights into memory deficits in depression

During a depressive episode, the ability of the brain to form new brain cells is reduced. Scientists of the Ruhr-Universität Bochum examined how this affects the memory with a computational model. It was previously known that people in an acute depressive episode were less likely to remember current events. The computational model however suggests that older memories were affected as […]

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Scientists help identify genetic markers for prostate cancer in global DNA download

An international team of researchers including USC scientists has found scores of new genetic markers in DNA code that increase prostate cancer risk—powerful knowledge likely to prove useful to detect and prevent the disease. Focusing on DNA of more than 140,000 men worldwide, researchers were able to identify 63 new genetic markers associated with prostate cancer risk. That greatly increases […]

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Reviving the protector—new tactic against medulloblastoma

Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in children. The results are scheduled for publication in Cancer Cell. Several emerging anticancer treatments are called “epigenetic therapies,” targeting the ways cancer cells shut off genes that could restrain their growth. The new tactic revives a protective gene called […]

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Possible new treatment for spinal cord injuries identified in animal studies

An experimental drug has shown promise as a potential therapy for spinal cord injuries in animal studies. The compound, 4-aminopyridine-3-methanol, works in a similar way as a drug previously developed at Purdue, 4-aminopyridine (4-AP), which has been approved by the U.S. Food and Drug Administration to treat multiple sclerosis. Dr. Riyi Shi, professor in the Department of Basic Medical Sciences, […]

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Visual worlds in mirror and glass

The clear, colorful rays of light characteristic of precious metals and jewels give us a rich sense of their quality. This is due to our ability to perceive materials, which provides an estimate of the surface condition and material of objects. Humans tend to attribute value to the phenomenon of light reflecting from or passing through the surface of an […]

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Hunger can lead to anger, but it’s more complicated than a drop in blood sugar, study says

What makes someone go from simply being hungry to full-on “hangry”? More than just a simple drop in blood sugar, this combination of hunger and anger may be a complicated emotional response involving an interplay of biology, personality and environmental cues, according to research published by the American Psychological Association. “We all know that hunger can sometimes affect our emotions […]

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