Are neurological disorders the result of brain evolution mistakes?

A team of researchers affiliated with several institutions in Australia has proposed that some neurological disorders might have their roots in evolutionary mistakes. In their paper published in the journal Nature Neuroscience, the group describes their ideas and possible paths of research moving forward. As scientists delve ever deeper into our brains as part of an effort to understand how […]

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Turmeric eye drops could treat glaucoma

A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma, finds a new study led by UCL and Imperial College London researchers. In the new Scientific Reports paper, the researchers report a new method to deliver curcumin, extracted from the yellow spice turmeric, directly to the back of the eye using eye drops, […]

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A new model to estimate lifetime risk of atherosclerotic cardiovascular disease

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality and also contributes to huge health care expenditures in China. Therefore, accurate and early identification of high-risk individuals is important for CVD prevention. The China-PAR (Prediction for atherosclerotic CVD (ASCVD) Risk in China) project generated equations with excellent capacity to predict lifetime risk for ASCVD by incorporating four large […]

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Study provides insight into how dying neurons control eating behaviors of the brain microglia

A new Mount Sinai study, published July 23 in the journal Nature Neuroscience, provides important insight into how microglia, cells that form a branch of the immune system inside the brain, go about their job of clearing out dying and non-functional neurons—and how they sometimes mistakenly attack healthy neurons, an event that can play a role in neurodegenerative diseases like […]

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Pregnancy and reproductive history may impact dementia risk

Research reported at the Alzheimer’s Association International Conference (AAIC) 2018 in Chicago highlighted sex differences associated with dementia and Alzheimer’s disease across the life course, including the first ever large-scale study of reproductive history and dementia risk in women. New results reported at AAIC 2018 suggest: Associations between dementia risk and number of children, number of miscarriages, age at first […]

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Large US study targets prostate cancer in black men

(HealthDay)—Black men in the United States have higher rates of aggressive prostate cancer than other males. Now, a $26.5 million study is underway to figure out why. The U.S. National Institutes of Health and the Prostate Cancer Foundation have launched the study to investigate social, environmental and genetic factors behind this disparity. “No group in the world is hit harder […]

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Greater efforts are needed to address ‘financial toxicity’ of cancer treatment

In addition to facing new concerns about their health, individuals who are diagnosed with cancer often worry about the financial burdens of treatment. A new study indicates that many patients feel that such ‘financial toxicity’ is not adequately addressed by their doctors and other clinicians. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer […]

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First practice guidelines for clinical evaluation of Alzheimer’s disease

Despite more than two decades of advances in diagnostic criteria and technology, symptoms of Alzheimer’s disease and Related Dementias (ADRD) too often go unrecognized or are misattributed, causing delays in appropriate diagnoses and care that are both harmful and costly. Contributing to the variability and inefficiency is the lack of multidisciplinary ADRD evaluation guidelines to inform U.S clinicians in primary […]

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Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments in cultured human cells reveal that blocking the protein reduces the characteristic sickling that distorts the shape of red blood cells and gives the disease its name. “We […]

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