Health Problems Archives - Page 117 of 202

Unique mechanism of action inhibiting paracellular phosphate absorption

31.08.2018 Health Problems

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. Tenapanor is a sodium/hydrogen exchanger 3 (NHE3) inhibitor currently being evaluated in a second Phase 3 registration trial, the PHREEDOM trial, for the treatment of hyperphosphatemia in patients with […]

Exposure to arsenic, lead, copper and cadmium linked to increased risk of heart disease

30.08.2018 Health Problems

Exposure to arsenic, lead, copper and cadmium is associated with an increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published by The BMJ today. In recent years, exposure to environmental toxic metals such as arsenic, lead, copper, and mercury have become a major global health concern. Arsenic and cadmium, for example, are […]

Genetic susceptibility to lower vitamin D levels and calcium intake not linked to fracture

30.08.2018 Health Problems

Having a genetic predisposition to lower vitamin D levels and calcium intake is not associated with an increased risk of osteoporotic fracture, conclude researchers in The BMJ today. Their findings add to the ongoing debate over the benefits for the general population of vitamin D supplementation, which is recommended by clinical guidelines to prevent fractures. The findings also back recent […]

Spinal muscular atrophy drug may be effective if started later than previously shown

30.08.2018 Health Problems

A drug shown to be effective in the treatment of babies with the rare muscle-wasting disease spinal muscular atrophy may be effective for muscle control even when treatment is started in children seven months and older, according to a study published in the August 29, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. Previous […]

CDC: greater awareness of valley fever needed nationally

30.08.2018 Health Problems

(HealthDay)—Greater nationwide awareness of the fungal infection Valley fever (coccidioidomycosis) is needed, according to a report published in the August issue of the U.S. Centers for Disease Control and Prevention’s Emerging Infectious Diseases. Kaitlin Benedict, from the CDC in Atlanta, and colleagues conducted enhanced surveillance in 14 states in 2016 by identifying coccidioidomycosis cases according to the Council of State […]

Quality of life after spinal cord injury—What functional abilities have the greatest impact?

29.08.2018 Health Problems

Independence in mobility is the single most important factor affecting quality of life in patients with traumatic spinal cord injury (TSCI), reports a study in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. Based on validated clinical questionnaires, the study by Julien Goulet, MD, and colleagues of Hôpital du Sacré-Coeur de […]

What’s that smell? Scientists find a new way to understand odors

29.08.2018 Health Problems

Every smell, from a rose to a smoky fire to a pungent fish, is composed of a mixture of odorant molecules that bind to protein receptors inside your nose. But scientists have struggled to understand exactly what makes each combination of odorant molecules smell the way it does or predict from its structure whether a molecule is pleasant, noxious or […]

Study shines light on cancer survival and a key gene mutation

29.08.2018 Health Problems

University of Toronto researchers have shone light on a well-known but mysterious gene that plays a key role in the growth of cancer. Genes contain blueprints for making proteins, the molecules that actually carry out tasks in a cell. The p53 gene helps make a protein known as p53, which tells cells to grow or not. This protein helps stop […]

Father’s diet could affect the long-term health of his offspring

29.08.2018 Health Problems

New research has shown that a lack of protein in a father’s diet affects sperm quality which can have a direct impact on the long-term health of their offspring. The study—’Paternal diet programs offspring health through sperm- and seminal plasma-specific pathways in mice’—carried out at the University of Nottingham fed male mice a poor quality diet which resulted in their […]

Effects of deep brain stimulation in patients with Parkinson’s disease

29.08.2018 Health Problems

Researchers at Universitätsmedizin Berlin have studied motor and cognitive effects of deep brain stimulation in patients with Parkinson’s disease. Their results show that the adverse cognitive effects of deep brain stimulation are linked to a different neural pathway than that responsible for the treatment’s desired motor effects. This finding will help optimize treatments for patients with Parkinson’s disease. Results from […]

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