Family history linked to early-onset A-fib in minorities

(HealthDay)—Probands of African or Hispanic/Latino descent with early-onset atrial fibrillation (EOAF) are more likely than European Americans to have a first-degree relative with AF, according to a study published online Sept. 21 in JAMA Network Open. Zain Alzahrani, M.D., from the University of Illinois at Chicago, and colleagues conducted a cohort study to examine the role of family history in […]

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Study: Improvement in glycemic parameters by adding dapagliflozin to metformin in T2D

Researchers used continuous glucose monitoring (CGM) to assess the effects of adding dapagliflozin to a regimen of either metformin or insulin in patients with type 2 diabetes (T2D) and found significant reductions in mean glucose and other glycemic factors, with greater improvements seen in patients taking metformin compared to insulin. The design and results of this trial are published in […]

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Human hair cells from a test tube

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin. This will make it possible to develop new treatment methods for hearing impairment in the future. About 5% of the world population suffers from hearing impairment. Disabling […]

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Preventable cardiovascular events are big economic burden

(HealthDay)—Preventable cardiovascular events place a considerable health and economic burden on the United States, according to research published in the Sept. 7 issue of the U.S. Centers for Disease Control and Prevention (CDC) Morbidity and Mortality Weekly Report. Matthew D. Ritchey, D.P.T., from the CDC in Atlanta, and colleagues used Healthcare Cost and Utilization Project databases to identify emergency department […]

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Doctors issue caution over missed cancer diagnoses tied to immune disorder

Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs—often causing death—doctors frequently pursue immediate treatment for the immune disorder after a […]

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Physical exercise improves the elimination of toxic proteins from muscles

A study published in Scientific Reports by researchers at the University of São Paulo (USP) in Brazil, in partnership with colleagues in the United States and Norway, shows that the lack of muscle stimulus results in a buildup of inadequately processed proteins in muscle cells and consequently leads to muscle weakness or wasting. This is a typical muscle dysfunction condition […]

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Hospital privacy curtains may harbor dangerous germs—new study

Without timely intervention, privacy curtains in hospitals can become breeding grounds for resistant bacteria, posing a threat to patient safety, according to new research published in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology (APIC). The longitudinal, prospective, pilot study tracked the contamination rate of ten freshly laundered privacy […]

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Can we teach heart cells to grow up?

Scientists around the world have been trying to replace damaged heart tissue using lab-made heart-muscle cells (cardiomyocytes), either injecting them into the heart or applying patches laced with the cells. But results to date have been underwhelming. “If you make cardiomyocytes in a dish from pluripotent stem cells, they will engraft in the heart and form muscle,” says William Pu, MD, […]

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