Fast-acting cholera vaccine could curb outbreaks

A tricked-out cholera vaccine starts protecting against the deadly disease within a day, experiments in rabbits suggest. The rapid protection offered by this designer vaccine may one day limit the spread of cholera outbreaks, says Howard Hughes Medical Institute (HHMI) Investigator Matthew Waldor. Waldor and his colleagues discovered an ability unique to the vaccine, called HaitiV: It protects rabbits from […]

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Tdap vaccine given during pregnancy reduces occurrence of infant pertussis

A study published today in the American Journal of Preventive Medicine shows the effectiveness of the Tdap (tetanus, diphtheria, acellular pertussis) vaccine for infants whose mothers receive the vaccine during pregnancy. The “Effectiveness of Prenatal Tetanus, Diphtheria, Acellular Pertussis Vaccination in the Prevention of Infant Pertussis in the U.S.” study led by Sylvia Becker-Dreps, MD, MPH, associate professor in the […]

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Finally, hope for a syphilis vaccine

Despite efforts to eradicate it, syphilis is on the rise. Until now, most health agencies focused on treating infected people and their sex partners but new discoveries may make a vaccine possible, UConn Health researchers report in the 12 June issue of mBio. The World Health Organization estimates that 10.7 million people between the ages of 15 and 49 had […]

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Addressing parents’ HPV vaccine hesitancy ups vaccination rates

(HealthDay)—Providers engaging parents hesitant about human papillomavirus (HPV) vaccination and addressing their concerns can lead to same-day vaccinations, according to a study published online May 15 in Pediatrics. Laura A. Shay, Ph.D., from the University of Texas in San Antonio, and colleagues audio-recorded 43 visits with unvaccinated adolescents at six pediatric clinics in which parents were undecided about HPV vaccination. […]

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Robust immune responses for herpes zoster subunit vaccine

(HealthDay)—Recipients of the herpes zoster subunit vaccine (HZ/su), consisting of varicella-zoster virus glycoprotein E (gE) and AS01B Adjuvant System, develop robust immune responses, according to a study published in the June 1 issue of The Journal of Infectious Diseases. Anthony L. Cunningham, M.D., from the University of Sydney, and colleagues presented immunogenicity results from two trials involving patients aged 50 […]

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Technology holds personalised cancer vaccine breakthrough

University of Queensland researchers have developed a vaccine delivery technology that enables treatment to be tailored precisely for different cancers. UQ’s Professor Ranjeny Thomas said the technology had the potential to improve the precision of cancer immunotherapy, leading to better cancer outcomes and reduce harmful side-effects. “Flexible cancer vaccines are a long-sought treatment strategy in cancer immunotherapy,” Professor Thomas said. […]

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Flu vaccine protects pregnant women against pertussis

Research by Wits scientists shows that pregnant women vaccinated against influenza also have less pertussis infection. Pertussis, also known as whooping cough, is a highly contagious respiratory disease caused by the bacterium Bordetella pertussis. Wits researchers at the MRC Respiratory and Meningeal Pathogens Research Unit (RMPRU) published a paper in the New England Journal of Medicine, which shows that pregnant […]

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