Adolescent cannabis use alters development of planning, self-control brain areas

Adolescent marijuana use may alter how neurons function in brain areas engaged in decision-making, planning and self-control, according to researchers at the University of Illinois at Chicago. The findings, which were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience, are the result of an animal model study focused on the structural development of the prefrontal cortex, […]

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Scientists uncover how rare gene mutation affects brain development and memory

Researchers from the University of California, Irvine School of Medicine, have found that a rare gene mutation alters brain development in mice, impairing memory and disrupting the communication between nerve cells. They also show memory problems could be improved by transplanting a specific type of nerve cell into the brain. The findings were published today in Neuron. “Mutations in hundreds […]

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Spying on the virus: Development to increase effectiveness of viral cancer therapy

Scientists have learned how to observe the processes of oncolytic viruses in cancer cells in real time. For the first time ever, a group of scientists from NUST MISIS and the University of Calgary (Canada) has applied intravital microscopy to study the interaction of oncolytic viruses with both tumor cells and healthy cells. With the technology, researchers can visualize how […]

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Blood vessels instruct brain development

Function and homeostasis of the brain relies on communication between its complex network of cells. Consequently, development of the different groups of cells in the brain needs to be coordinated in time and space. The group of Amparo Acker-Palmer (Buchmann Institute of Molecular Life Sciences and the Institute of Cell Biology and Neuroscience, Goethe University) reported in the last issue […]

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Newly identified drug target in rheumatoid arthritis paves way for development of new therapies

University of Melbourne researchers have identified a protein involved in rheumatoid arthritis-induced inflammation that could lead to new drug treatments for people who do not respond to current therapies. Arthritis is Australia’s most common chronic disease and affects more than 3.5 million people. Rheumatoid arthritis (RA) affects about one per cent of the population and is one of the most […]

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Changes to specific MicroRNA involved in development of Lou Gehrig’s disease

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS). The research focuses on a specific microRNA whose levels were found to decrease as a result of ALS-causing muscular mutations. The study highlights, for the first time, the importance of toxic muscle-secreting molecules in the pathology […]

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