DDW: Psych disorders make GERD hard to Dx by symptoms alone

(HealthDay)—For patients with minor psychiatric disorders (MPD), symptoms of gastroesophageal reflux disease (GERD) are unreliable for establishing the presence of GERD, according to a study presented at the 2018 Digestive Disease Week, held from June 2 to 5 in Washington, D.C. Rafael Laurino Neto, M.D., from the Federal University of Sao Paulo in Brazil, and colleagues conducted a prospective study […]

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Cervical cancer may be driven by imbalance in vaginal bacteria, research finds

Virtually all cervical cancers are caused by HPV, or human papillomavirus, dubbed the “common cold” of sexually transmitted infections because nearly every sexually active person catches it. Fortunately, the immune system vanquishes the majority of HPV infections, with only a small percentage progressing to precancer and, ultimately, cancer. But why do some people clear the infection while others are unable […]

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Operating on brain gliomas by detecting the ‘glow’

Research by Barrow Neurological Institute physicians and University of Washington scientists on novel imaging technology for malignant brain tumors was published in the April issue of World Neurosurgery. The research was conducted by Drs. Evgenii Belykh and Mark Preul at the Barrow Neurological Institute Neurosurgery Research Laboratory with technology developed by Drs. Eric Seibel and Leonard Nelson from the Department […]

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By 2030, prostate and lung cancers expected to be most common cancers among HIV population

Despite declines in cancer incidence rates among HIV-infected people, cancer will remain a significant concern as this patient population ages. By 2030, prostate and lung cancers are projected to be the most common cancers among individuals aging with HIV. The findings are published in Annals of Internal Medicine. Due to their weakened immune systems, people living with HIV have a […]

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EPO protects preemies’ brains by modifying genes essential for generating new brain cells

Erythropoietin (EPO) helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so. Genetic analyses conducted by a multi-institutional research team finds that EPO may work its neuroprotective magic by modifying genes essential for regulating growth and development of nervous tissue as well as genes that respond to inflammation and hypoxia. Findings from […]

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PD-L1 expression in medulloblastoma: An evaluation by subgroup

This study evaluated the expression of PD-L1 and markers of immune mediated resistance in human medulloblastoma, the most common malignant pediatric brain tumor. In cell lines, SHH MB, which are low-MYC expressing, demonstrated both constitutive and inducible expression of PD-L1 while those in Group 3/4 that expressed high levels of MYC had only inducible expression. MB expresses low levels of […]

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Brick by brick—assembly of the measles virus

Researchers have been able to capture images of measles viruses as they emerge from infected cells, using state of the art cryo-electron tomography techniques. The new images will help with a greater understanding of measles and related viruses, and could give hints on antiviral drug strategies likely to work across multiple viruses of this type. The results were published Monday, […]

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Imagined and actual movements are controlled by the brain in the same way

A new study from Karolinska Institutet in Sweden shows that imagined movements can change our perception in the same way as real, executed movements do. The research, which is presented in the scientific journal Nature Communications, contributes to an increased understanding of how mental training works and may be useful for patients with motor disabilities. “Mental training is very beneficial […]

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Selection of a pyrethroid metabolic enzyme CYP9K1 by malaria control activities

Researchers from LSTM, with partners from a number of international institutions, have shown the rapid selection of a novel P450 enzyme leading to insecticide resistance in a major malaria vector. In a paper published in PNAS the team of researchers led by LSTM’s Professor Janet Hemingway describe how operational malaria control activities, and a move back to pyrethroid based indoor […]

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