Engineered DNA vaccine protects against emerging Mayaro virus

Infections by the mosquito-borne Mayaro virus (MAYV) have largely been restricted to people who ventured into the heavily forested areas of Trinidad and Tobago and neighboring regions of South America. However, recent laboratory studies showing additional mosquito vectors can transmit MAYV as well as a reported case of MAYV infection in Haiti in 2015, reveal the potential for the virus […]

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A proposal to reduce vaccine exemptions while respecting rights of conscience

Vaccine resistance is one of the top 10 threats to global health in 2019, according to the World Health Organization. Here in the U.S., New York City is currently experiencing its worst outbreak of measles in decades, sickening scores of children in ultra-Orthodox Jewish neighborhoods. Other clustered outbreaks of deadly and highly contagious, but vaccine-preventable, diseases are becoming frustratingly routine […]

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Research suggests path to vaccine or drug for late-onset Alzheimer’s

UT Southwestern researchers have succeeded in neutralizing what they believe is a primary factor in late-onset Alzheimer’s disease, opening the door to development of a drug that could be administered before age 40, and taken for life, to potentially prevent the disease in 50 to 80 percent of at-risk adults. Apolipoprotein E (ApoE) is a protein that carries fatty substances […]

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Analysis finds HPV vaccine safe

Infection with human papillomavirus (HPV) can cause certain cancers in women and men, but HPV vaccines are highly effective in preventing infection with oncogenic HPV types. A new British Journal of Clinical Pharmacology review of post-licensure data did not identify any new or unexpected safety concerns of the bivalent HPV vaccine. The authors analyzed reports submitted to the Vaccine Adverse […]

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Find the flu vaccine that’s right for you

School’s back in session, which means that germs that are carrying illnesses such as influenza can start to spread rapidly among classmates, and to their families outside of school. But the good news is that with a variety of flu vaccination options, almost everyone can find just the right one for their needs, says an expert at Baylor College of […]

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Human microbiome influences rotavirus vaccine response

In a proof-of-concept study in healthy adult men, scientists in the Netherlands found that microbiome manipulation with antibiotics influenced the response to oral rotavirus vaccine. Specifically, they found higher levels of viral shedding in those receiving antibiotic treatment prior to vaccination compared with controls receiving no antibiotic treatment prior to vaccination. The study is a human demonstration that altering the […]

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Fast-acting cholera vaccine could curb outbreaks

A tricked-out cholera vaccine starts protecting against the deadly disease within a day, experiments in rabbits suggest. The rapid protection offered by this designer vaccine may one day limit the spread of cholera outbreaks, says Howard Hughes Medical Institute (HHMI) Investigator Matthew Waldor. Waldor and his colleagues discovered an ability unique to the vaccine, called HaitiV: It protects rabbits from […]

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