Results of early-stage liver cancer detection using liquid biopsy published

Today, Proceedings of the National Academy of Sciences (PNAS) published the results of a pilot study for early detection of liver cancer in a cohort of HBV carriers at risk for developing the disease. This screening technology, known as HCCscreen, relies on detecting a combination of tumor-specific mutations in cell free DNA (cfDNA) and protein markers. This work was a […]

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Using light to stop itch

Itch is easily one of the most annoying sensations. For chronic skin diseases like eczema, it’s a major symptom. Although it gives temporary relief, scratching only makes things worse because it can cause skin damage, additional inflammation and even more itch. EMBL researchers have now found a way to stop itch with light in mice. Nature Biomedical Engineering publishes their […]

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Treating COPD patients for anxiety using CBT reduces hospital visits and is cost-effective

Cognitive behavioural therapy (CBT) delivered by respiratory nurses is cost-effective and reduces anxiety symptoms in chronic obstructive pulmonary disease (COPD) patients, according to research published in ERJ Open Research. COPD is a long-term condition that causes inflammation in the lungs, narrowing of the airways and damaged lung tissue, making breathing difficult. Anxiety often occurs alongside COPD and can mean that […]

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Using the microbiome to help premature babies grow

About half of babies born prematurely struggle to grow, putting them at risk of health problems that can last a lifetime. Despite years of research, physicians lack a method that consistently helps these infants thrive. A study suggests that the gut microbiome – the trillions of tiny bacteria that live in the digestive tract – could help doctors personalize nutrients […]

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Using light to fight GVHD

Extracorporeal photopheresis (ECP) is used to treat chronic graft-versus-host disease (cGVHD)—a complication of bone marrow or stem cell transplant that occurs when donor cells attack the recipient. How ECP works is unclear, and standardized treatment guidelines have not been established. Vanderbilt medical student Jocelyn Gandelman, Madan Jagasia, MBBS, and colleagues conducted a prospective, multicenter clinical trial of ECP for cGVHD. […]

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Using DeepMind’s neural network learning system to diagnose eye diseases

Three institutions working together have applied DeepMind’s neural network learning system to the task of discovering and diagnosing eye diseases. Moorfields Eye Hospital has been working with Google’s DeepMind Health subsidiary and University College London in the effort, and have documented their progress in a paper published in Nature Medicine. As the researchers note, eye doctors currently use a machine […]

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Using hepatitis C-infected donor kidneys could reduce time on dialysis for transplant patients with HCV

Transplanting hepatitis C (HCV)-infected dialysis patients with organs from HCV-positive donors and then treating the infection after transplantation is more effective, costs less and will shorten wait times for donated organs, according to a computer analysis conducted by physician-researchers at the University of Cincinnati (UC) College of Medicine. The findings are available online in the Annals of Internal Medicine. The […]

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Diagnostics of genetic cardiac diseases using stem cell-derived cardiomyocytes

A new study by Professors Martti Juhola and Katriina Aalto-Setälä of the University of Tampere in Finland demonstrates that with the use of artificial intelligence and machine learning, it is possible not only to accurately sort sick cardiac cell cultures from healthy ones, but also to differentiate between genetic cardiac diseases. iPSC-derived cardiomyocytes can be derived from a blood sample […]

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Using AI to detect heart disease

Heart disease is the leading cause of death for both men and women, according to the Centers for Disease Control and Prevention (CDC). In the U.S., one in every four deaths is a result of heart disease, which includes a range of conditions from arrhythmias, or abnormal heart rhythms, to defects, as well as blood vessel diseases, more commonly known […]

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