Specialist technique used to study drugs completed for first time during Ebola outbreak

A specialist technique used to study drugs has been completed for the first time during an outbreak of Ebola virus disease. The study published today in eBiomedicine was a collaboration of researchers from Sierra Leone and the University’s of Glasgow, Oxford, Cambridge and the Liverpool School of Tropical Medicine. It used pharmacokinetics—the measurement of the change in drug concentration in […]

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Second Ebola vaccine to be used in DR Congo next month

Doctors will use a second Ebola vaccine from November in three eastern provinces in the Democratic Republic of Congo to fight the deadly virus, medical officials said Sunday. “It’s time to use the new Ad26-ZEBOV-GP vaccine, manufactured by Johnson & Johnson’s Belgian subsidiary,” said Dr. Jean-Jacques Muyembe, who leads the national anti-Ebola operation in the DRC. It will arrive in […]

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CRISPR used to reduce symptoms of muscular dystrophy in mice models

A team of researchers from Canada, the U.S. and Sweden has found that editing a gene involved in producing proteins that promote muscle strength in muscular dystrophy mice models could reduce symptoms. In their paper published in the journal Nature, the group describes their experiments with mice and what they learned from them. Muscular dystrophy is an inherited condition in […]

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New stem cell model can be used to test treatments for a rare nervous system disorder

A City of Hope researcher has developed a stem cell model to assess possible treatments for a rare nervous system disorder that is in the same disease group as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). The finding takes Yanhong Shi, Ph.D., senior author of the study, and her colleagues one step closer to finding a way to […]

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Lipid molecules can be used for cancer growth

When the blood supply is low, cancer cells can use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumour models by researchers at Karolinska Institutet, Sweden, in a study published in Cell Metabolism. The mechanism may explain why tumours often develop resistance to cancer drugs that inhibit the formation of blood vessels. Tumour growth […]

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Liquid nicotine used in e-cigarettes still a danger to children despite recent decline in exposures

A new study published online today by Pediatrics and conducted by the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children’s Hospital found that there were more than 8,200 calls to US poison centers regarding exposures to liquid nicotine and e-cigarettes among children younger than 6 years of age from January 2012 through April […]

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