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Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing. These findings, published today in eLife, may help clinicians to identify cancer patients at risk of metastasis, a process where cancer cells spread to other parts of the body. They […]
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Brain imaging of veterans with Gulf War illness show varying abnormalities after moderate exercise that can be categorized into two distinct groups—an outcome that suggests a more complex illness that previously thought. Researchers at Georgetown University Medical Center, using functional magnetic resonance imaging (fMRI), have shown the Gulf War Illness patients have one of two different of kinds of changes […]
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Researchers have discovered that instances in which outcomes are better than expected—finding an unexpectedly good parking spot, for example, or spotting a $20 bill on the sidewalk—improves memories of specific events. This is in addition to the long-established role that unexpectedly good outcomes have in influencing what are called integrated memories. Remembering where you parked your car this morning is […]
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Researchers at the University of North Carolina School of Medicine used MRI brain scans and machine learning techniques at birth to predict cognitive development at age 2 years with 95 percent accuracy. “This prediction could help identify children at risk for poor cognitive development shortly after birth with high accuracy,” said senior author John H. Gilmore, MD, Thad and Alice […]
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Researchers at Duke-NUS Medical School have demonstrated for the first time a physical interaction between two types of immune cells that plays an important role in the early fight against dengue virus infection. Dengue virus is widespread in the tropics and is transmitted by mosquitos. Dengue virus infection incidence has grown dramatically in recent years, with estimates suggesting 390 million […]
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(HealthDay)—Two drugs have been approved by the U.S. Food and Drug Administration for the treatment of rare blood diseases, the agency announced Friday. Elzonris (tagraxofusp-erzs) infusion was granted the first approval for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adults and children aged 2 years and older. Researchers investigated the efficacy of Elzonris in two patient cohorts […]
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New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalised medicine ever nearer. Professor Laura van ‘t Veer, leader of the Breast Oncology Program at the University of California San Francisco, USA, told the […]
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After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments. The molecules promote full recovery after traumatic brain injury (TBI) in mice, according to the study published online in Neurobiology of Disease. Traumatic brain injury is the leading cause of […]
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(HealthDay)—For patients who experienced a transient ischemic attack (TIA) or minor stroke, the rate of a composite of stroke, acute coronary syndrome, or death from cardiovascular causes is 12.9 percent at five years, with half of these events occurring in the second through fifth years, according to a study published June 7 in the New England Journal of Medicine. Pierre […]
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Two teams of researchers, one working in the U.S., the other in Italy, have come up with new ways to avert cytokine release syndrome (CRS) in leukemia patients who undergo CAR T-cell therapies. In the first, the researchers working at the Sloan Kettering Cancer Center in New York developed a mouse model to replicate the conditions under which CRS develops. […]
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