Researchers engineer T cells to recognize tumor-specific expression patterns, enhancing tumor response

The advent and advancement of T cell therapy, especially chimeric antigen receptor (CAR)-modified T cells, has demonstrated therapeutic potential in treating previously treatment-resistant tumors. However, few CAR targets are absolutely tumor-specific, resulting in “on-target, off-tumor” toxicities that can be severe. Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist […]

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Why the eye could be the window to brain degeneration such as Alzheimer’s disease

Researchers from Queen’s University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer’s disease (AD). This research results have recently been published in the Journal of Ophthalmic Research and is the first clinical study showing a potential for peripheral retinal imaging to be used in monitoring AD and potentially other […]

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South Africa’s battle to resuscitate cancer care

South African electrician Phiwankosi Mkhize was diagnosed with lung cancer in May last year and told by the hospital to come back for a scan in 15 months. But after just 12 months he died, before having the chance to receive treatment. The 66-year-old’s fate is far from unique in southeastern KwaZulu-Natal province, the country’s second most populous. Hundreds of […]

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New cellular pathway helps explain how inflammation leads to artery disease

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis—deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide. “We have known for decades that atherosclerosis is a disease of […]

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CPR is key to survival of sudden cardiac arrest

Cardiopulmonary resuscitation increases the possibility of surviving sudden cardiac arrest. But it’s not just trained professionals who can jump in to perform CPR. There are simple, life-saving steps any bystander can take. “We think it should be a basic life skill,” such as knowing to call 911 when there’s a fire, said Dr. Clifton Callaway, a professor and executive vice […]

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Eva Longoria Rallies to Keep Kids With Their Parents Shortly After Giving Birth

Actor Eva Longoria gave birth to her first child, Santiago Enrique Bastón, on Tuesday — and in between snuggle sessions, she’s using her platform to rally against the Trump administration’s zero-tolerance immigration policy.  "In light of my son’s birth I wanted to bring focus on the families that have been separated at the border," Longoria captioned her first publicly shared […]

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Researchers report novel method to quickly make therapeutic proteins from human blood

UMBC researchers report novel method to quickly make therapeutic proteins from human blood Personalized medicine has incredible potential, but current approaches are still too expensive and time-consuming to have a big impact. A new paper in Scientific Reports looks at how to extract cellular protein synthesis machinery from human blood, and, by adding recombinant DNA to the extract, to produce […]

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Scientists discover how brain signals travel to drive language performance

Effective verbal communication depends on one’s ability to retrieve and select the appropriate words to convey an intended meaning. For many, this process is instinctive, but for someone who has suffered a stroke or another type of brain damage, communicating even the most basic message can be arduous. Scientists know that a brain region called the left inferior frontal gyrus […]

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