Switching to certain antidiabetic drugs linked to increased risk of major complications

For people with type 2 diabetes, switching to sulfonylurea drugs to control blood sugar levels is associated with an increased risk of complications compared with staying on the drug metformin, finds a study in The BMJ today. As such, the researchers say that continuing metformin when introducing sulfonylureas is safer than switching. Metformin is a “first-line” therapy (the first drug […]

Continue reading »

New guidelines to diagnose, manage rare endocrine disorders

International guidelines have been published for the first time to help doctors around the globe diagnose and manage patients with a very rare set of endocrine diseases known as pseudohypoparathyroidism and its related disorders, including Albright hereditary osteodystrophy (AHO). It’s the realization of a long-term goal for physician-scientist Dr. Emily Germain-Lee of the UConn School of Medicine and Connecticut Children’s […]

Continue reading »

Study results may lead to improved diagnostics for breast cancer

A study in Molecular Oncology indicates that examining the protein and RNA in leftover materials from routine diagnostic tests for breast cancer may lead to more accurate diagnoses. Using samples from fine needle aspiration from 25 patients with breast cancer and 33 patients with benign lesions, investigators found that such a strategy could distinguish all cancer patient samples from all […]

Continue reading »

Supermodel Kate Upton Is Going to Be a Mom

Supermodels and pro athletes go together like chocolate and peanut butter, right? So we weren’t that surprised when Kate Upton married Justin Verlander last November in Tuscany because that’s just what you do when you’re a model and a Houston Astros pitcher in love. We were, however, surprised to find out this morning that the pair is expecting their first […]

Continue reading »

The brain distinguishes causes of errors to perform adaptation

Practice is necessary to improve motor skills. Even if one performs poorly at first, one’s athletic performance improves through repeated exercise due to the reduction of motor errors as the brain learns. However, it’s important to remember that there are two types of errors: motor errors caused by poor motor control and target errors caused by unexpected target movements. For […]

Continue reading »

A 3-pronged plan to cut type 2 diabetes risk

(HealthDay)—The type 2 diabetes tide remains unchecked in the United States, as does pre-diabetes—having a blood sugar level higher than normal, but not high enough for a diabetes diagnosis. A U.S. Centers for Disease Control and Prevention report found that about 30 million Americans—roughly 10 percent of the population—have type 2 diabetes. What’s more, over 80 million have pre-diabetes, which, […]

Continue reading »

Why randomized trials for proton therapy are difficult to complete (and what we can do about it)

Randomized clinical trials are the gold standard of cancer research and can shed light on whether innovative, new therapies with great potential actually have clear benefits over usual care for patients. However, the seven randomized trials funded by the National Cancer Institute (NCI) and the Patient Centered Outcomes Research Institute (PCORI) to test proton therapy are enrolling more slowly than […]

Continue reading »
1 37 38 39 40 41 60