targeted Archives - Family Medicine News

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

04.12.2019 Health Problems

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study. “This agent has shown in clinical trials to be effective in delaying cancer growth beyond established […]

How DNA outside cells can be targeted to prevent the spread of cancer

11.07.2019 Health Problems

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. Scientists from Tokyo University of Science, led by Prof Ryushin Mizuta, have now discovered exactly how cfDNA is generated. They also talk about the applications of DNase1L3—the enzyme mainly responsible for generating cfDNA—as a novel molecule to prevent the spread of tumors. Prof […]

Experts call for a targeted approach to cancer prevention

01.11.2018 Health Problems

Policymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at the University of Stirling. A new paper – published in the International Journal of Healthcare Policy – analysed data from 162 countries to examine the relationship between economic growth and cancer incidence. Dr. Bryan McIntosh, of the Faculty of […]

Cancer: More targeted use of immunotherapy

12.06.2018 Health Problems

Doctors are increasingly fighting cancer by stimulating patients’ immune systems. SNSF-supported researchers have now discovered a method for predicting the likelihood of treatment success. Immunotherapy changes a patient’s immune system to allow it to attack cancer cells and either destroy them or at least keep them from growing. But the therapy only works for a minority of patients. Researchers supported […]

Targeted radiotherapy for breast cancer offers good quality of life and fewer side effects

22.04.2018 Health Problems

Quality of life for women treated with a more targeted radiotherapy treatment – called accelerated partial breast irradiation – is at least as good as quality of life for women treated with standard radiotherapy, according to research presented at the ESTRO 37 conference and published simultaneously in The Lancet Oncology. The treatment uses small tubes to deliver a higher dose […]

First-in-human clinical trial of new targeted therapy drug reports promising responses for multiple

15.04.2018 Health Problems

A phase I, first-in-human study led by The University of Texas MD Anderson Cancer Center reveals for the first time, an investigational drug that is effective and safe for patients with cancers caused by an alteration in the receptor tyrosine kinase known as RET. The drug appears to be promising as a potential therapy for RET-driven cancers, such as medullary […]

Mathematical modeling offers new way to understand variable responses to targeted therapy

03.04.2018 Health Problems

Cancer therapies that target a specific protein have improved outcomes for patients. However, many patients eventually develop resistance to these targeted therapies and their cancer comes back. It is believed that differences among tumor cells, or heterogeneity, may contribute to this drug resistance. Moffitt Cancer Center researchers are using a unique approach by combining typical cell culture studies with mathematical […]