Disruption of glycine receptors to study embryonic development and brain function

Glycine receptors are among the most widely distributed inhibitory receptors in the central nervous system and have important roles in a variety of physiological processes. Researchers from Max Planck Florida Institute for Neuroscience (MPFI), University of Toyama, Yamagata University, Cairo University, RIKEN Center for Integrative Medical Sciences and Setsunan University collaborated to study glycine receptors, particularly glycine receptor alpha-4 (Glra4), […]

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Study examines causes of death in US breast cancer survivors

Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients with breast cancer. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Of […]

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Veterans study suggest two sub-types of Gulf War illness

Brain imaging of veterans with Gulf War illness show varying abnormalities after moderate exercise that can be categorized into two distinct groups—an outcome that suggests a more complex illness that previously thought. Researchers at Georgetown University Medical Center, using functional magnetic resonance imaging (fMRI), have shown the Gulf War Illness patients have one of two different of kinds of changes […]

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New study provides insight into chronic kidney disease

Researchers have further analyzed a known signaling pathway they believe brings them one step closer to understanding the complex physiology of patients with chronic kidney disease (CKD), which might provide a path to new treatment options. CKD is a complex and unique condition that involves impaired removal of many different toxins from the blood. These toxins, which often are referred […]

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Study finds problems with gestational diabetes test in rural areas

A number of pregnant women in rural and remote areas may be missing out on being diagnosed with gestational diabetes due to problems with blood testing, according to new research by The University of Western Australia, Kimberley Aboriginal Medical Services and member services. Associate Professor Julia Marley from UWA’s Medical School said it was possible that two out three women […]

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Study provides insights into how fibrosis progresses in the human lung

A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease. The study, led by Naftali Kaminski, M.D., the Boehringer-Ingelheim Endowed Professor of Internal Medicine and chief of the Section of Pulmonary, Critical Care, and Sleep Medicine at Yale School of […]

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Study: Multidisciplinary transplantation evaluation shows promise for older adults

Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. The study, which reported on a multidisciplinary clinic (MDC) at the University of Chicago Medical Center, found that patients treated with this approach experienced better transplantation outcomes and survival rates. Most blood cancers that can […]

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Study vaccine protects monkeys against four types of hemorrhagic fever viruses

Scientists funded by the National Institutes of Health have developed an investigational vaccine that protected cynomolgus macaques against four types of hemorrhagic fever viruses endemic to overlapping regions in Africa. The University of Texas Medical Branch in Galveston and Profectus BioSciences of New York are developing and testing the candidate quadrivalent VesiculoVax vaccine, with support from NIH’s National Institute of […]

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Most comprehensive study of genetic, sudden-death heart condition posts first results

Researchers have revealed the initial results from the world’s largest comprehensive study of hypertrophic cardiomyopathy, an abnormal thickening of the heart that often goes undiagnosed and can prove deadly. The condition can present at any age, and it is the most common cause of sudden cardiac death in young athletes. The early findings from the $14.4 million study suggest that […]

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