Mouse study links early metastasis to systemic inflammation caused by wound healing

According to new research conducted in mice by Whitehead Institute scientists, surgery in breast cancer patients, which while often curative, may trigger a systemic immunosuppressive response, allowing the outgrowth of dormant cancer cells at distant sites whose ability to generate tumors had previously been kept in check by the immune system. Taking a non-steroidal anti-inflammatory drug (NSAID) around the time […]

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Teachers can help reduce mental health problems in children, study finds

School-based mental health services delivered by teachers and staff can significantly reduce mental health problems in elementary-aged children, according to a new study by researchers at the Florida International University Center for Children and Families. The implications are significant considering approximately 30 to 40 percent of youth in the U.S. will be diagnosed with at least one mental health disorder […]

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Study may show how chronic early-life stress raises PTSD vulnerability

A collaboration between investigators at Massachusetts General Hospital and Khyber Medical University in Pakistan may have discovered how chronic stress experienced early in life increases vulnerability to post-traumatic stress disorder (PTSD) later in life. In their report published in Translational Psychiatry the researchers describe finding that chronic stress induces a persistent increase in the hormone ghrelin, both in a rat […]

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For first time, ALSPAC study charting children of the ’90s available to researchers

For the first time, the history charting the world-renowned Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the ’90s, back to its beginnings has been made accessible. The work, made possible thanks to a Wellcome grant and a dedicated team of archivists from the University’s Special Collections, will mean that researchers can now access the […]

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Study: Almost 100 million adults have COPD in China

Chronic obstructive pulmonary disease (COPD) is widespread in China with 8.6 percent of the country’s adult population – almost 100 million people -suffering from the chronic lung disease, according to a new Tulane University study published in The Lancet. The study, which provided lung-function screenings for more than 50,990 participants, is the largest survey of COPD across age groups ever […]

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Study finds how fat tissue shunts energy to tumors

Obesity is the second-leading preventable cause of cancer and represents one of the greatest threats to global human health. But it has not been clear exactly how whole-body metabolism affects tumor formation. In particular, the molecular mechanisms by which fat cells communicate with tumor tissue remain poorly understood. Sanford Prebys Medical Discovery Institute (SBP) researchers recently addressed this question, revealing […]

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Sunshine could hold clues on the timing for a severe form of heart attack, study says

The sun’s radiation could be a factor in seasonal patterns of a deadly type of heart attack, according to new research that tracked a “summer shift” in their occurrence across seven countries. Previous research has examined how these attacks – called ST-elevation myocardial infarctions, or STEMIs – seem to happen most often in the daytime during the colder winter months, […]

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Study confirms that inflammation during pregnancy is linked to baby’s brain

Inflammation is a normal part of the body’s response to infection, chronic stress or obesity. In pregnant women, it is believed that heightened inflammation increases the risk of mental illness or brain development problems in children. A study conducted by researchers at OHSU in Portland, Oregon, has established a link between inflammation in pregnant women and the way the newborn […]

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Study locates circadian clock that controls daily rhythms of aggression

Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome – a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness, the circadian clock exerts control […]

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