Study of acute myeloid leukemia patients shows protein inhibitor drug safe and effective with durable remissions

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease. The multi-center Phase I trial, led by researchers at The University of Texas MD Anderson Cancer Center, was designed to determine ivosidenib’s safety and […]

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Heavier women may face higher cancer risks, study finds

(HealthDay)—Excessive weight gain is never a good idea for health. Now, new research supports the notion that putting on pounds raises cancer risks for middle-aged women. The study, which tracked more than 137,000 Norwegian women for 18 years, found that the odds of developing certain cancers rose as waistlines expanded. The take-home message: “maintaining stable weight in middle adulthood … […]

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Selective neural connections can be reestablished in retina after injury, study finds

The brain’s ability to form new neural connections, called neuroplasticity, is crucial to recovery from some types of brain injury, but this process is hard to study and remains poorly understood. A new study of neural circuit repair in the retina shows that neurons can make new connections to the right types of photoreceptors to restore selective connectivity after an […]

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Long-term psychological study confirms time is the best medicine against homesickness

Time heals homesickness – and quickly, according to a unique long-term study on international students. A propensity towards neuroticism and the desire to keep others happy are among the factors associated with the development of homesickness. However, the study also found that the level of homesickness among those currently studying abroad is generally low. The investigation was facilitated by a […]

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Study finds vitamin D supplement decreases wheezing for black preterm infants

African American infants born prematurely are at higher risk for recurrent wheezing. This condition can cause the baby discomfort and is a risk factor for developing asthma later in life. There are no widely-accepted therapies to prevent prematurity-associated wheezing. In a first-of-its-kind study published in the Journal of the American Medical Association (JAMA), an University Hospitals Rainbow Babies & Children’s […]

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New study provides rationale for use of a multi-target anticancer drug in patients with malignant pleural mesothelioma

The multi-target small molecule anticancer drug nintedanib shows promising effectiveness in stopping the growth of human malignant pleural mesothelioma, a fatal thoracic tumor, in preclinical models, according to a new study published jointly by researchers in Austria, Germany and Hungary. Malignant pleural mesothelioma is a particularly aggressive tumor that occurs in the lining that covers the lungs. It typically results […]

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