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Samantha A. Morris, PhD, an assistant professor of developmental biology and of genetics at Washington University School of Medicine in St. Louis, has received the New York Stem Cell Foundation’s Robertson Stem Cell Investigator Award. She is one of three investigators receiving the award this year. It recognizes outstanding early-career scientists and provides each $1.5 million over five years to […]
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Social scientists have long worked to understand the roots of racial prejudice in the U.S., and for years, the story went like this: As different groups are exposed to others, their prejudice against those others increases. Brian O’Shea wasn’t buying it. A postdoctoral fellow working in the lab of Matt Nock, the Edgar Pierce Professor of Psychology, O’Shea is the […]
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Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes a toll on intestinal stem cells and may contribute to increased susceptibility to disorders of the gastrointestinal tract. The researchers also showed […]
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Brain stem cells in people with the most severe form of multiple sclerosis look much older than they really are, according to a study led by UConn Health and published in the Proceedings of the National Academy of Sciences (PNAS). The prematurely old cells act differently in the brain than normal ones, and could be the key to new treatments […]
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Scientists have identified two distinct control mechanisms in the developmental transition of undifferentiated stem cells into healthy brain cells. This fundamental research using mice may inform regenerative medicine treatments for neurodegenerative diseases and spinal cord injuries, in the future. When an embryo develops, stem cells differentiate into all the types of cells that the adult will need. Neural stem cells […]
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Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather, the location of DNA mutations is relevant. Using the mutation patterns in hematopoietic stem and progenitor cells (HSPCs), the team was able to trace the developmental lineage tree of the cells. Van Boxtel, […]
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In 2006, a few hundred mostly local researchers gathered in La Jolla to discuss the emerging but still science-fictiony field of stem cells. Since then, stem cells, enhanced by gene therapy, have progressed to yield breakthrough treatments, most spectacularly in cancer. Likewise, the conference known as the Cell & Gene Meeting on the Mesa has mushroomed into an international event. […]
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Tissues grown in the lab from stem cells may fail to live up their therapeutic promise because the cells choose their own fate. For the last 20 years, scientists have worked to engineer tissues for use in a range of conditions, such as osteoarthritis or heart failure. They do this by placing stem cells – those that can become any […]
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UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues—which line all of the organs and cavities inside the body—and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a […]
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Myocardial infarction – commonly known as a heart attack – is still one of the main causes of death. According to the Federal Statistical Office, more than 49,00 people died of its consequences. And yet the mortality after heart attack has greatly decreased over the past decades: As compared to the early 1990s, it has more than halved until 2015, […]
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