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For decades, neuroscientists have relied on a technique for reading out electrical “spikes” of brain activity in live, behaving subjects that tells them very little about the types of cells they are monitoring. In a new study, researchers at the University of Tuebingen and MIT’s Picower Institute for Learning and Memory demonstrate a way to increase their insight by distinguishing […]
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CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded to other treatments. But until now, the underlying biological pathways enabling anti-cancer responses have not been thoroughly examined. Understanding these pathways is important for designing future generations of CAR T-cell therapies, including reducing side effects, preventing […]
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As many as 50 percent of human cancer cases—across a wide variety of tissues—involve defects in a common cellular growth signaling pathway. These defects have so far defied most attempts to develop targeted therapies, leading some in the field to conclude that they may be “undruggable.” Now researchers at UC San Francisco and Redwood City-based Revolution Medicines, Inc, have identified […]
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Effective verbal communication depends on one’s ability to retrieve and select the appropriate words to convey an intended meaning. For many, this process is instinctive, but for someone who has suffered a stroke or another type of brain damage, communicating even the most basic message can be arduous. Scientists know that a brain region called the left inferior frontal gyrus […]
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Scientists in the USA have developed a new deep brain stimulation method to treat the symptoms of Parkinson’s disease. While present deep brain stimulation for Parkinson’s is constant, the new method is ‘adaptive’. This means the stimulation changes in real time, based on the patient’s neural signals. The study, published today in the Journal of Neural Engineering, used brief in-clinic […]
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