signaling Archives - Family Medicine News

A common insulin signaling pathway across cancer and diabetes

04.12.2019 Health Problems

An oncology researcher has made an unexpected contribution to the understanding of type 2 diabetes. In results published in Science Advances, Patrick Hu, M.D., associate professor of medicine at Vanderbilt University Medical Center, found a protein that modulates a signaling pathway often targeted by cancer therapies is also required for insulin biogenesis. Hu and colleagues showed a protein controlling the […]

Important signaling pathway in breast cancer revealed

25.01.2019 Health Problems

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences (PNAS) that a particular signaling pathway in breast cancer tumors causes cancer cells to divide symmetrically, expanding the tumor. Inhibiting the pathway with drugs could become a strategy for eliminating the cancer cells. In breast cancer, one of the most common cancers in women, tumors contain a […]

Researcher: Big data, networks identify cell signaling pathways in lung cancer

23.05.2018 Health Problems

A team of scientists led by University of Montana cell biologist Mark Grimes has identified networks inside lung cancer cells that will help understand this cancer and fight it with drug treatments. The paper, published as the cover article of the May 22 issue of Science Signaling, sheds light on how a new class of drugs called HSP90 inhibitors—which are […]