Probing the role of an inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules—including one called resolvin D1—play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood. There is a receptor on the surface of many immune cells called ALX/FRP2, and in models of atherosclerosis, ALX/FPR2 is known to act as a […]

Continue reading »

Engineers create delicate sensor to monitor heart cells with minimal disruption

For the first time, engineers have demonstrated an electronic device to monitor beating heart cells without affecting their behavior. A collaboration between the University of Tokyo, Tokyo Women’s Medical University and RIKEN in Japan produced a functional sample of heart cells with a soft nanomesh sensor in direct contact with the tissue. This device could aid study of other cells, […]

Continue reading »