CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types. Scientists at the Wellcome Sanger Institute and the Broad Institute of MIT and Harvard compared the consistency of the two datasets, independently verifying the methodology and findings. The […]

Continue reading »

Too much screen time for the kids? Grandparents may also be complicit

Grandparents have long been associated with letting their grandchildren do things their parents would never permit. Candy. Extended bedtime. Too much television. Carefree fun. They like to spoil their grandchildren. A new study by Rutgers and other researchers finds that today’s grandparents are still true to their traditional fun-loving image—allowing their grandchildren, while under their supervision, to spend about half […]

Continue reading »

Screen time—even before bed—has little impact on teen well-being: study

Data from more than 17,000 teenagers show little evidence of a relationship between screen time and well-being in adolescents. The study, published in Psychological Science, a journal of the Association for Psychological Science, casts doubt on the widely accepted notion that spending time online, gaming, or watching TV, especially before bedtime, can damage young people’s mental health. “Implementing best practice […]

Continue reading »

Why screen time can disrupt sleep—scientists uncover how certain retinal cells respond to artificial illumination

For most, the time spent staring at screens—on computers, phones, iPads—constitutes many hours and can often disrupt sleep. Now, Salk Institute researchers have pinpointed how certain cells in the eye process ambient light and reset our internal clocks, the daily cycles of physiological processes known as the circadian rhythm. When these cells are exposed to artificial light late into the […]

Continue reading »

Women’s Preventive Services Initiative says screen all women annually for urinary incontinence

All women should be screened annually for urinary incontinence, according to new guidelines from the Women’s Preventive Services Initiative (WPSI). Screening should assess whether women experience urinary incontinence and whether it affects their activities and quality of life. If treatment is indicated, women should be referred for further evaluation. The clinical guideline and evidence review are published in Annals of […]

Continue reading »

Scientists screen molecules for promise as new prostate cancer drugs

Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be developed into new anti-cancer drugs. The research team from the Departments of Pharmacy & Pharmacology and Chemistry are studying a protein called α-methylacyl-CoA racemase (AMACR) as a potential […]

Continue reading »