Scientists discover how superbugs hide from their host

New research led by the University of Sheffield has discovered how a hospital superbug evades the immune system to cause infection – paving the way for new treatments. The study, led by the University of Sheffield’s Department of Molecular Biology and Biotechnology, investigated how Enterococcus faecalis (E. faecalis), bacteria commonly found in the digestive tracts of humans, cause life-threatening infections. […]

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Scientists restore some functions in a pig’s brain hours after death

Circulation and cellular activity were restored in a pig’s brain four hours after its death, a finding that challenges long-held assumptions about the timing and irreversible nature of the cessation of some brain functions after death, Yale scientists report April 18 in the journal Nature. The brain of a postmortem pig obtained from a meatpacking plant was isolated and circulated […]

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Scientists uncover novel strategy to target common type of cancer

Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife. The findings, originally posted on bioRxiv, suggest that targeting a protein called Werner syndrome helicase (WRN) could represent a novel opportunity for treating a subgroup of cancer patients with microsatellite instability-high (MSI-H) tumors. MSI is a […]

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Scientists make strides in creation of clinical-grade bone

A team of scientists from the New York Stem Cell Foundation (NYSCF) Research Institute reported Friday in Stem Cell Research and Therapy that they have made valuable progress toward creating clinical-grade cells for treatment of bone disease and injury. In their study, the team identified two types of growth media that could support effective expansion of mesenchymal progenitor (MP) cells […]

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New drug slashes death rates among drug-resistant TB patients: scientists

Credit: CC0 Public Domain A new treatment for a deadly drug-resistant strain of tuberculosis can cure more than 90 percent of sufferers, according to a landmark clinical trial whose results were revealed exclusively to AFP. Doctors in Belarus—a country with one of the world’s highest rates of multidrug-resistant tuberculosis—treated 181 patients with the new drug, bedaquiline, in combination with other […]

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Scientists uncover how rare gene mutation affects brain development and memory

Researchers from the University of California, Irvine School of Medicine, have found that a rare gene mutation alters brain development in mice, impairing memory and disrupting the communication between nerve cells. They also show memory problems could be improved by transplanting a specific type of nerve cell into the brain. The findings were published today in Neuron. “Mutations in hundreds […]

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